药代动力学的研究重点。
Research priorities in pharmacokinetics.
作者信息
Tucker Geoffrey T
机构信息
Simcyp Ltd, Blades Enterprise Centre, John St, Sheffield S24SU, UK.
出版信息
Br J Clin Pharmacol. 2012 Jun;73(6):924-6. doi: 10.1111/j.1365-2125.2012.04238.x.
Abstract
An opinion is expressed on the past, present and future roles of pharmacokinetic-pharmacodynamic research in the context of UK clinical pharmacology. On the basis of its current constitution, it seems unlikely that this area of research will be driven from within academic clinical pharmacology in the UK. Therefore, in order to bring its expertise and experience to bear effectively on the evolving emphasis on translational medicine and modelling and simulation, this community would need to reach out beyond its current preoccupations to increase interactions with the next generation of pharmacokineticists and pharmacometricians.
摘要
本文就药代动力学-药效学研究在英国临床药理学背景下的过去、现在和未来作用发表了观点。基于其目前的构成，该研究领域似乎不太可能由英国学术临床药理学内部推动。因此，为了有效地将其专业知识和经验应用于对转化医学以及建模与模拟日益增长的重视上，这个群体需要超越其当前关注的范围，加强与下一代药代动力学家和药物计量学家的互动。
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