Hsieh Ming-Yun, Ponsford Jennie, Wong Dana, Schönberger Michael, McKay Adam, Haines Kerrie
School of Psychology and Psychiatry, Monash University, Melbourne, Australia.
Brain Inj. 2012;26(2):126-38. doi: 10.3109/02699052.2011.635365.
CBT is a potentially effective treatment for anxiety disorders following TBI; however, empirical evidence has mainly come from clients with mild TBI. This paper describes a CBT-based anxiety treatment programme adapted for clients with more severe injuries. Two case studies are provided to illustrate the implementation of the programme, as a step toward larger scale testing of the programme's feasibility.
A manualised adapted CBT treatment manual was used to deliver CBT in a standardised manner to two clients, one with severe and one with moderate TBI. Outcome was evaluated using a single-subject design with repeated measures of anxiety, mood and coping style at pre- and post-CBT.
The two clients demonstrated positive treatment response on either a measure of anxiety or a continuous measure of distress. Although neither demonstrated a clinically significant change according to the primary outcome measure (Hospital Anxiety and Depression Scale), they showed significant change in at least one corroborated measure of anxiety.
This study suggests the potential utility of the adapted CBT programme for clients with moderate-severe TBI. Limitations of the single case studies were discussed, while noting how they would be addressed in a follow-up randomised controlled trial.
认知行为疗法(CBT)是治疗创伤性脑损伤(TBI)后焦虑症的一种潜在有效方法;然而,实证证据主要来自轻度创伤性脑损伤患者。本文描述了一种基于认知行为疗法的焦虑治疗方案,该方案适用于伤势更严重的患者。提供了两个案例研究来说明该方案的实施情况,作为对该方案可行性进行更大规模测试的一个步骤。
使用一份经过改编的认知行为疗法手册,以标准化方式对两名患者实施认知行为疗法,一名是重度创伤性脑损伤患者,另一名是中度创伤性脑损伤患者。采用单病例设计,在认知行为疗法前后对焦虑、情绪和应对方式进行重复测量,以评估治疗效果。
两名患者在焦虑测量或痛苦程度连续测量方面均表现出积极的治疗反应。虽然根据主要结局指标(医院焦虑抑郁量表),两人均未表现出具有临床意义的变化,但他们在至少一项焦虑佐证指标上显示出显著变化。
本研究表明,改编后的认知行为疗法方案对中重度创伤性脑损伤患者具有潜在效用。讨论了单病例研究的局限性,同时指出将如何在后续的随机对照试验中解决这些问题。