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[巨细胞病毒围产期感染所致婴幼儿血小板减少性紫癜]

[Thrombocytopenic purpura of the young infant caused by perinatal infection by cytomegaloviruses].

作者信息

Taboada Liewald H, Campbell Bull M, Osses Montesinos M, Pruyas Artieda M, Vergara Rojas M I

出版信息

Bol Med Hosp Infant Mex. 1979 Jul-Aug;36(4):743-55.

PMID:223606
Abstract

Two cases of idiopathic trombocytopenic purpura, in infants 37 and 42 days old, and one case of atypical congenital cytomegaloviral disease are presented, the latter proved at necropsy. Cytomegalic inclusion cells are found in urine in both cases of purpura with hepatosplenomegaly and mononucleosis syndrome. In one of the cases, cytomegalovirus cultures are positive in urine and blood. The hemorrhagic syndrome is mild and recuperation is achieved in less than thirty days, without relapse. The use of corticosteroids is not recommended. With these two new cases, thirteen similar clinical observation of thrombocytopenic purpura in infants, six of them in 1977, are completed. Thus, a new entity is added to the growing list of clinical manifestations caused by human CMV infection.

摘要

本文报告了两例37天和42天大婴儿的特发性血小板减少性紫癜,以及一例非典型先天性巨细胞病毒病,后者经尸检证实。在两例伴有肝脾肿大和单核细胞增多综合征的紫癜病例的尿液中均发现了巨细胞包涵体细胞。其中一例,尿液和血液中的巨细胞病毒培养呈阳性。出血综合征较轻,不到三十天即可康复,且无复发。不建议使用皮质类固醇。加上这两例新病例,完成了13例婴儿血小板减少性紫癜的类似临床观察,其中6例发生在1977年。因此,人类巨细胞病毒感染引起的临床表现不断增加的清单中又增加了一个新的病种。

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Bol Med Hosp Infant Mex. 1979 Jul-Aug;36(4):743-55.
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