BIOS/Lab-on-Chip Group, MESA+ Institute for Nanotechnology, University of Twente, P. O. Box 217, 7500 AE Enschede, The Netherlands.
Lab Chip. 2012 Apr 21;12(8):1548-53. doi: 10.1039/c2lc21233a. Epub 2012 Feb 24.
In this paper an easy to fabricate SU8/glass-based microfluidic sensor is described with two closely spaced parallel electrodes for highly selective measurements using the redox cycling effect. By varying the length of the microfluidic entrance channel, a diffusion barrier is created for non-cycling species effectively increasing selectivity for redox cycling species. Using this sensor, a redox cycling amplification of ∼6500× is measured using the ferrocyanide redox couple. Moreover, a simple, but accurate analytical expression is derived that predicts the amplification factor based on the sensor geometry.
本文介绍了一种易于制造的 SU8/玻璃基微流控传感器，该传感器具有两个紧密间隔的平行电极，可利用氧化还原循环效应进行高度选择性测量。通过改变微流体入口通道的长度，为非循环物质创建扩散障碍，从而有效提高氧化还原循环物质的选择性。使用该传感器，使用亚铁氰化物氧化还原对测量到约 6500×的氧化还原循环放大。此外，还推导出了一个简单但准确的分析表达式，该表达式基于传感器几何形状预测放大因子。
