用于无标记、高灵敏度电化学检测病原体 DNA 的背景电流降低和生物条形码扩增。
Background current reduction and biobarcode amplification for label-free, highly sensitive electrochemical detection of pathogenic DNA.
机构信息
Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China.
出版信息
Chem Commun (Camb). 2012 Apr 4;48(27):3309-11. doi: 10.1039/c2cc18107j. Epub 2012 Feb 23.
PMID:22362204
Abstract
By using exonuclease I and biobarcode nanoparticles, we describe a novel background current reduction strategy for amplified electrochemical detection of uropathogen specific sequences at ultralow concentrations.
摘要
利用核酸外切酶 I 和生物条形码纳米粒子，我们描述了一种新颖的背景电流降低策略，用于在超低浓度下扩增电化学检测尿病原体特异性序列。
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