Zöckler N, Rief W, Kühl K, Kenn K
Philipps-Universität Marburg, AG Klinische Psychologie und Psychotherapie, Marburg, Germany.
Pneumologie. 2012 May;66(5):290-6. doi: 10.1055/s-0031-1291636. Epub 2012 Feb 23.
The aim of the present study was to analyze the associations between COPD-specific anxiety and depressive symptoms in COPD patients. Anxiety, as well as depression, is a prevalent comorbid complication in COPD. Either can have a negative impact on patients' experience and the course of disease. So far, assessment in studies has exclusively focused on anxiety in general and not on disease-related fears. The present study comprised a sample of ninety-six patients suffering from COPD (GOLD III/IV). Results of the MANOVA showed higher COPD-specific anxiety in patients with depressive symptoms than in patients without depressive symptoms. Depressive patients showed a higher fear of social isolation, dyspnea related fear, fear of movement and fear of progression of disease. There were no differences between the two groups with regard to functional parameters (FEV 1 % pred.; 6-minute-walk-test). Overall, our study shows the necessity of the assessment of COPD-specific fears related to depression to guarantee an adequate treatment.
本研究的目的是分析慢性阻塞性肺疾病（COPD）患者中COPD特异性焦虑与抑郁症状之间的关联。焦虑以及抑郁是COPD中常见的共病并发症。二者均会对患者的体验和病程产生负面影响。到目前为止，研究评估仅关注一般焦虑，而非与疾病相关的恐惧。本研究纳入了96例COPD（全球慢性阻塞性肺疾病倡议III/IV级）患者样本。多变量方差分析结果显示，有抑郁症状的患者比无抑郁症状的患者存在更高的COPD特异性焦虑。抑郁患者表现出对社会隔离、呼吸困难相关、运动及疾病进展的更高恐惧。两组在功能参数（预计第一秒用力呼气容积百分比；6分钟步行试验）方面无差异。总体而言，我们的研究表明有必要评估与抑郁相关的COPD特异性恐惧，以确保进行充分治疗。
