Stenzel N, Rief W, Kühl K, Pinzer S, Kenn K
Philipps-Universität Marburg, AG Klinische Psychologie und Psychotherapie.
Pneumologie. 2012 Feb;66(2):111-8. doi: 10.1055/s-0031-1291637. Epub 2012 Feb 15.
Anxiety and depression are prevalent comorbid conditions in COPD. Furthermore, diseases related anxieties (fear of progression, end-of-life fear) occur very often. Anxiety can have a negative impact on patients' quality of life and is sometimes even considered as a risk factor for re-hospitalisation. There are only a few studies that focus on disease related anxieties in COPD. The aim of our study was to investigate the associations between disease related anxieties (fear of progression, end-of-life fear), psychological health status and quality of life in COPD patients. 132 patients with COPD (GOLD II-IV) participated in the study. Results of a MANOVA showed no differences between diseases related anxieties among patients with different disease severity (GOLD II-IV). Furthermore, the results showed significant associations between end-of-life fear, fear of progression, depression and quality of life. Further analyses showed that there is a need for managing end-of-life fears and improving end-of-life care. Overall, our study showed, that health disease related anxieties play an important role in COPD and still do not receive enough attention.
焦虑和抑郁是慢性阻塞性肺疾病（COPD）中普遍存在的共病情况。此外，与疾病相关的焦虑（对病情进展的恐惧、对临终的恐惧）也很常见。焦虑会对患者的生活质量产生负面影响，有时甚至被视为再次住院的风险因素。仅有少数研究关注COPD中与疾病相关的焦虑。我们研究的目的是调查COPD患者中与疾病相关的焦虑（对病情进展的恐惧、对临终的恐惧）、心理健康状况和生活质量之间的关联。132例COPD（全球慢性阻塞性肺疾病倡议[GOLD]分级II - IV级）患者参与了该研究。多变量方差分析（MANOVA）结果显示，不同疾病严重程度（GOLD II - IV级）患者之间与疾病相关的焦虑没有差异。此外，结果显示临终恐惧、病情进展恐惧、抑郁和生活质量之间存在显著关联。进一步分析表明，需要处理临终恐惧并改善临终关怀。总体而言，我们的研究表明，与健康疾病相关的焦虑在COPD中起着重要作用，但仍未得到足够的关注。
