Connor N P, Abbs J H
Waisman Center on Mental Retardation and Human Development, University of Wisconsin-Madison 53705-2280.
Phys Ther. 1990 Dec;70(12):864-72. doi: 10.1093/ptj/70.12.864.
In the last decade, a great deal of research has been aimed at ascertaining the manner in which the basal ganglia (BG) contribute to the control of movement. The formation of workable hypotheses, however, has been limited by the great variety of putative roles reported in the literature. Reported functions have often been in direct conflict. Recent developments, however, provide new perspectives from which to view seemingly discordant functions. Data reviewed in this article suggest a distinct anatomical topography within the BG, allowing for highly specialized subfunctions. In parallel, BG cellular activity has been found primarily in association with specific sensory and task-related dimensions relevant to particular movements. The multiple sensorimotor contributions of the BG therefore are not contradictory, but represent BG contributions within different functional contexts. These multiple roles of the BG offer particular clinical insights.
在过去十年中，大量研究致力于确定基底神经节（BG）对运动控制的作用方式。然而，可行假设的形成受到文献中报道的多种假定作用的限制。所报道的功能常常直接相互冲突。不过，最近的进展提供了新的视角，可用于审视看似不一致的功能。本文所综述的数据表明，BG内部存在独特的解剖学拓扑结构，从而允许高度专业化的子功能。与此同时，已发现BG细胞活动主要与特定运动相关的特定感觉和任务相关维度有关。因此，BG的多种感觉运动作用并非相互矛盾，而是代表了BG在不同功能背景下的作用。BG的这些多种作用提供了独特的临床见解。
