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脑转移瘤内形成脓肿。

Abscess formation within brain metastasis.

作者信息

Martínez Emilio González, Piaggio Giancarlo Daniel Mattos

机构信息

Department of Neurological Surgery, University Hospital of León, León, Spain.

出版信息

Surg Neurol Int. 2025 Jun 13;16:236. doi: 10.25259/SNI_62_2025. eCollection 2025.

Abstract

BACKGROUND

Brain abscesses are a potentially curable but life-threatening medical condition. Their occurrence within brain metastases has been exceptionally reported. In this study, we describe in detail this rare entity.

CASE DESCRIPTION

A previously healthy 64-year-old female was referred to our neurosurgical department with right-sided deviation of the oral commissure and a 7-day history of holocranial headache. Magnetic resonance imaging revealed a tumor in the right frontal lobe, exhibiting an iso-intense signal on T1-weighted images with heterogeneous enhancement. On diffusion-weighted imaging, the lesion displayed a hyperintense signal. A body computed tomography scan identified a lung tumor in the left superior lobe and a potential metastasis in the right adrenal gland. Intraoperative findings and histopathological examination revealed metastasis from lung adenocarcinoma. In addition, purulent content was noted within the abscess, and cultures identified and .

CONCLUSION

Abscess formation within metastases is rarely diagnosed preoperatively, primarily because these lesions do not present with characteristic clinical or radiological features. Early recognition of this entity is crucial for establishing an appropriate treatment plan.

摘要

背景

脑脓肿是一种有潜在治愈可能但危及生命的疾病。脑转移瘤内出现脑脓肿的情况鲜有报道。在本研究中,我们详细描述了这一罕见病例。

病例描述

一名64岁既往健康的女性因口角向右侧偏斜及全颅头痛7天被转诊至我们的神经外科。磁共振成像显示右侧额叶有一个肿瘤,在T1加权图像上呈等信号,强化不均匀。在扩散加权成像上,该病变呈高信号。全身计算机断层扫描发现左上叶有一个肺部肿瘤,右肾上腺有一个可能的转移灶。术中发现及组织病理学检查显示为肺腺癌转移。此外,脓肿内发现脓性内容物,培养鉴定出……

结论

转移瘤内的脓肿形成术前很少被诊断出来,主要是因为这些病变没有典型的临床或影像学特征。早期识别这一实体对于制定合适的治疗方案至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5501/12255205/4188ed000aef/SNI-16-236-g001.jpg

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