Osborn M F, Gath D H
University Department of Psychiatry, Warneford Hospital, Oxford.
Psychol Med. 1990 Aug;20(3):565-72. doi: 10.1017/s0033291700017062.
The aim was to study women before and after hysterectomy (with conservation of the ovaries), in order to discover how far premenstrual symptoms are caused physically and how far psychologically. In such women both physical and psychological factors can influence premenstrual symptoms before hysterectomy; after the operation, in the absence of menstruation, only physical factors can do so. The subjects were 56 women awaiting hysterectomy for menorrhagia of benign origin. During three pre-operative months these women made daily self-ratings on a check-list in which typical premenstrual symptoms were interspersed with atypical symptoms; in this way their awareness of the premenstrual focus was minimized. Starting six months after hysterectomy, the women again kept daily check-lists for three months; over the same period their serum progesterone levels were measured to identify the premenstruum. After hysterectomy, levels of premenstrual symptoms fell significantly in the whole group, indicating that psychological factors were important determinants of such symptoms before hysterectomy.
本研究旨在对子宫切除术后（保留卵巢）的女性进行术前和术后研究，以确定经前症状在多大程度上是由生理因素引起的，又在多大程度上是由心理因素引起的。对于此类女性，生理和心理因素在子宫切除术前均可影响经前症状；而术后，由于不再有月经，只有生理因素能够产生影响。研究对象为56名因良性原因导致月经过多而等待子宫切除术的女性。在术前的三个月里，这些女性每天根据一份检查表进行自我评分，检查表中典型的经前症状与非典型症状穿插出现；通过这种方式，将她们对经前关注点的意识降至最低。从子宫切除术后六个月开始，这些女性再次连续三个月每天填写检查表；在同一时期，测量她们的血清孕酮水平以确定经前期。子宫切除术后，整个组的经前症状水平显著下降，这表明心理因素是子宫切除术前此类症状的重要决定因素。
