Dowlatshahi D, Paykel E S
Department of Psychiatry, University of Cambridge.
Psychol Med. 1990 Aug;20(3):655-62. doi: 10.1017/s0033291700017177.
Thirty-three patients admitted to hospital with severe early onset puerperal psychiatric disorders were compared with matched normal puerperal controls. Interviews, which were administered after recovery, covered life events in the previous thirteen months and detailed assessment of previous and personal history, pregnancy and labour, other aspects of stress, social support, and marital relationships. No differences, except for previous history of psychiatric disorder, were found between patients and controls or between patients with depressive and with other diagnoses. These findings of absence of social stress contrast with previous studies of milder post-partum depression and of disorders with onset during pregnancy, and suggest that the aetiology of severe post-partum disorders is predominantly biological.
33例因严重早发型产褥期精神障碍入院的患者与匹配的正常产褥期对照组进行了比较。康复后进行访谈，内容涵盖前13个月的生活事件以及对既往史和个人史、妊娠与分娩、其他压力因素、社会支持和婚姻关系的详细评估。除了既往精神障碍史外，患者与对照组之间或抑郁患者与其他诊断患者之间均未发现差异。这些无社会压力的研究结果与先前关于较轻产后抑郁症和孕期发病障碍的研究形成对比，表明严重产后障碍的病因主要是生物学因素。
