Lee Kyung-Hak, Ryu Se Min, Park Sung-Min, Park Hyun Seok, Lee Kang Hoon, Cho Seong-Joon
Department of Thoracic and Cardiovascular Surgery, Kangwon National University Hospital, Kangwon National University School of Medicine, Korea.
Korean J Thorac Cardiovasc Surg. 2012 Feb;45(1):56-9. doi: 10.5090/kjtcs.2012.45.1.56. Epub 2012 Feb 7.
Aspergillus is a ubiquitous fungus and can cause many levels of disease severity. Chronic necrotizing aspergillosis is a rare disease and few cases have been reported in Korea. We experienced a case of pleural aspergillosis that was treated successfully with medical and surgical interventions. The 52-year-old man who was diagnosed with chronic necrotizing pulmonary aspergillosis underwent surgical treatment including a lobectomy, decortication, and myoplasty. The patient was also medically treated with amphotericin B followed by voriconazole. Pleural irrigation with amphotericin B was also performed. A multi-dimensional approach should be considered for treating chronic necrotizing pulmonary aspergillosis.
曲霉菌是一种广泛存在的真菌,可导致多种严重程度的疾病。慢性坏死性曲霉菌病是一种罕见疾病,韩国报道的病例较少。我们诊治了一例经内科和外科干预成功治愈的胸膜曲霉菌病病例。一名被诊断为慢性坏死性肺曲霉菌病的52岁男性接受了包括肺叶切除术、纤维板剥脱术和肌成形术在内的手术治疗。该患者还接受了两性霉素B治疗,随后使用伏立康唑。同时还进行了两性霉素B胸腔灌洗。治疗慢性坏死性肺曲霉菌病应考虑采用多维度方法。