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[乳糜泻女性的生殖系统疾病:病因特异性治疗的效果]

[Reproductive disorders in women with celiac disease: effect of etiotropic therapy].

作者信息

Bykova S V

出版信息

Eksp Klin Gastroenterol. 2011(7):116-21.

PMID:22364010
Abstract

The study included 132 women (average age 38.5 +/- 1.17 years) with HC observed in the CSRIG from 2000 to 2010. Comparison group consisted of 105 women (average age 38.7 +/- 1.6 years) mainly with functional bowel disorders (irritable bowel syndrome, functional constipation, functional meteorism, inert colon). Take into account the information relating to obstetric and gynecological history, Physical and laboratory signs of malabsorption syndrome (MS), studies of antibodies to alpha-gliadin immunoglobulin (IG), Class A (AHA) and tissue transglutaminase (AtTG). Reproductive disorders in women with celiac disease are significantly more frequently than in women with functional bowel disease. One of the causes of reproductive disorders in patients with HC might be malabsorption disorders of essential nutrients in the small intestine. The presence of reproductive disorders should be considered as a risk factor for celiac disease, so these women should be screened for celiac disease.

摘要

该研究纳入了2000年至2010年期间在CSRIG观察到的132名患有HC的女性(平均年龄38.5±1.17岁)。对照组由105名女性(平均年龄38.7±1.6岁)组成,主要患有功能性肠病(肠易激综合征、功能性便秘、功能性腹胀、惰性结肠)。考虑到与妇产科病史、吸收不良综合征(MS)的体格和实验室体征、抗α-麦醇溶蛋白免疫球蛋白(IG)、A类(AHA)和组织转谷氨酰胺酶(AtTG)抗体的研究相关的信息。患有乳糜泻的女性生殖系统疾病比患有功能性肠病的女性更为常见。HC患者生殖系统疾病的原因之一可能是小肠中必需营养素的吸收不良。生殖系统疾病的存在应被视为乳糜泻的一个危险因素,因此应对这些女性进行乳糜泻筛查。

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[Reproductive disorders in women with celiac disease. Effect of the etiotropic therapy].
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