Jacobsson Lisa Ring, Friedrichsen Maria, Göransson Anne, Hallert Claes
Department of Social and Welfare Studies, Faculty of Health Sciences, Linköping University, Norrköping, Sweden.
Gastroenterol Nurs. 2012 May-Jun;35(3):200-6. doi: 10.1097/SGA.0b013e318255fe3a.
Despite living with a gluten-free diet, Swedish women with celiac disease report a higher rate of gastrointestinal symptoms than women without the disease. This study was designed to assess the impact of active patient education on gastrointestinal symptoms in women with a gluten-free diet. A total of 106 Swedish women, aged 20 years or older, with celiac disease on a gluten-free diet for a minimum of 5 years took part in a randomized controlled trial. The intervention group (n = 54) underwent a 10-session educational program, "Celiac School," based on problem-based learning. Controls (n = 52) were sent information regarding celiac disease at home. The outcome measure was gastrointestinal symptoms at 10 weeks and 6 months after intervention, assessed with the Gastrointestinal Symptom Rating Scale. After 10 weeks of "Celiac School," the participating women reported significant improvements that remained 6 months later (p = .029). The controls did not improve significantly. A comparison of the development of scores, from baseline to 10 weeks, could not demonstrate a significant difference in the overall index between the 2 groups but showed a significant improvement concerning 1 of its components, namely the index reflecting Abdominal Pain (p = .007). Intervention methods should be refined to reach an even more pronounced effect.
尽管采用无麸质饮食，但患有乳糜泻的瑞典女性报告的胃肠道症状发生率高于未患该病的女性。本研究旨在评估积极的患者教育对采用无麸质饮食的女性胃肠道症状的影响。共有106名年龄在20岁及以上、患有乳糜泻且采用无麸质饮食至少5年的瑞典女性参与了一项随机对照试验。干预组（n = 54）参加了一个基于问题式学习的为期10节的教育项目“乳糜泻学校”。对照组（n = 52）在家中收到有关乳糜泻的信息。结局指标是干预后10周和6个月时的胃肠道症状，采用胃肠道症状评分量表进行评估。经过10周的“乳糜泻学校”课程后，参与的女性报告有显著改善，且6个月后仍保持（p = .029）。对照组没有显著改善。比较两组从基线到10周的得分变化，两组在总体指数上没有显著差异，但在其一个组成部分，即反映腹痛的指数方面有显著改善（p = .007）。应改进干预方法以达到更显著的效果。
