Quiroga-Garza Alejandro, Delgado-Brito Miriam, Bazaldúa-Cruz Juan José, Villarreal-Silva Eliud, Velázquez-Gauna Sergio E, Elizondo-Omaña Rodrigo E, Guzmán-López Santos
Departamento de Anatomia Humana, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, NL.
Rev Invest Clin. 2011 Jul-Aug;63(4):399-406.
Animal models have been developed for the study of the intimal hyperplasia, a common cause of venous graft stenosis.
To establish a venous graft animal model for the study of the morphologic adaptative response to the arterial circulation.
A venous graft was placed in the arterial circulation of the caudal extremity from Wistar rats. In order to develop the model, it was carried out a morphologic study of the caudal extremity blood vessels. Three possible sites were evaluated for the obtaining of the venous graft.
Graft permeability and viability were observed only in one segment, between the muscular branches and the origin of the saphenous vein. The portion of vein that was obtained from one extremity, was placed in the arterial circulation of the opposite extremity.
A venous graft animal model was established, using a femoral vein segment, between the muscular branches and the origin of the saphenous vein, placing it in the homonyme artery of the opposite extremity.
已建立动物模型用于研究内膜增生，这是静脉移植物狭窄的常见原因。
建立一种静脉移植物动物模型，用于研究对动脉循环的形态适应性反应。
将一段静脉移植物置于Wistar大鼠尾端的动脉循环中。为建立该模型，对尾端血管进行了形态学研究。评估了三个可能获取静脉移植物的部位。
仅在肌肉分支与隐静脉起始部之间的一个节段观察到移植物的通透性和活力。从一个肢体获取的静脉段被置于对侧肢体的动脉循环中。
利用股静脉在肌肉分支与隐静脉起始部之间的节段，将其置于对侧同名动脉中，建立了一种静脉移植物动物模型。
