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尼泊尔春季角结膜炎概况:一项基于医院的研究。

Profile of vernal keratoconjunctivitis in Nepal: a hospital based study.

作者信息

Kansakar I

机构信息

Shree Rana Ambika Shah Eye Hospital, Lumbini Eye Institute, Bhairahawa, Nepal.

出版信息

Nepal Med Coll J. 2011 Jun;13(2):92-5.

PMID:22364089
Abstract

Vernal keratoconjunctivitis (VKC) or Spring Catarrh is recurrent, chronic, allergic conjunctivitis occurring in prepubertal age-group during spring and summer season. Though this is a self-limiting disorder, it often leads to visual impairment due to secondary corneal complications if not treated during active stage of the illness. Apart from this, the illness is known to affect the productivity and quality of life in school going children due to absenteeism and limitations to outdoor activities. Knowing the clinical profile of disease would provide the evidence for developing, treatment protocol in coming years. Therefore a hospital based study was designed to see the profile of VKC. Total of 220 patients were enrolled in this study. Male to female ratio with VKC was found to be 4:1. Clinical presentation showed seasonal variation; 78.2% during the spring and summer season. Bilateral involvement was seen in 100% cases, out of which 44.5% were limbal type. The best spectacle corrected visual status of better than 6/9 was in 96.4%, while 2.3% had vision less than 6/12. In 9.5% corneal involvement was seen as superficial keratopathy, while others, such as Shield ulcer, pannus, corneal scar, and keratoconus consisted of 8.3%. The disease is predominantly seen in male child with seasonal variation. Visual impairment is mainly due to involvement of cornea.

摘要

春季角结膜炎(VKC)或春季卡他性结膜炎是一种复发性、慢性过敏性结膜炎,发生于青春期前年龄组的春夏季。虽然这是一种自限性疾病,但如果在疾病活动期未得到治疗,常因继发性角膜并发症导致视力损害。除此之外,由于旷课和户外活动受限,已知该疾病会影响学龄儿童的学习效率和生活质量。了解该疾病的临床特征将为未来制定治疗方案提供依据。因此,设计了一项基于医院的研究来观察VKC的特征。本研究共纳入220例患者。VKC患者的男女比例为4:1。临床表现呈季节性变化;78.2%发生在春夏季。100%的病例为双侧受累,其中44.5%为角膜缘型。最佳矫正视力优于6/9的患者占96.4%,而2.3%的患者视力低于6/12。9.5%的患者出现角膜浅层病变,其他如盾形溃疡、血管翳、角膜瘢痕和圆锥角膜占8.3%。该疾病主要见于男性儿童,具有季节性变化。视力损害主要是由于角膜受累。

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Korean J Ophthalmol. 2024 Oct;38(5):364-374. doi: 10.3341/kjo.2024.0048. Epub 2024 Aug 16.
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Allergic conjunctivitis.过敏性结膜炎
Community Eye Health. 2017;30(99):S7-S10.