Ghimire P, Sah A K
Department of Radiology and Nuclear Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, PR China.
Nepal Med Coll J. 2011 Jun;13(2):142-3.
18F-fluorodeoxyglucose positron emission tomography (FDG-PET) has been widely incorporated in cancer management. Although, it has increased sensitivity, 18F-FDG is not tissue specific thus posing diagnostic dilemma in certain situations. False positivity in pulmonary nodules have been seen in various inflammatory, infective as well as post operative conditions while false negativity is common with adenomas, low grade lymphomas, bronchoalveolar carcinomas and carcinoid tumors. We present two cases of granulomatous diseases as pulmonary cryptococcosis and tuberculosis showing false positivity in a resected colorectal cancer patient and highlight the importance of recognition of this entity in an endemic region for granulomatous infections.
18F-氟脱氧葡萄糖正电子发射断层扫描（FDG-PET）已广泛应用于癌症管理。尽管18F-FDG的敏感性有所提高，但它并非组织特异性的，因此在某些情况下会造成诊断困境。在各种炎症、感染以及术后情况下，肺结节中都可见假阳性，而腺瘤、低度淋巴瘤、支气管肺泡癌和类癌肿瘤则常见假阴性。我们报告了两例肉芽肿性疾病，即肺隐球菌病和肺结核，在一名接受手术切除的结直肠癌患者中显示出假阳性，并强调了在肉芽肿性感染流行地区识别这一实体的重要性。
