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免疫功能正常患者的肺部隐球菌病酷似血源转移性病变:正电子发射断层扫描/计算机断层扫描(PET/CT)示无 18F-氟脱氧葡萄糖摄取的价值。

Case of pulmonary cryptococcosis mimicking hematogeneous metastases in an immunocompetent patient: value of absent 18F-fluorodeoxyglucose uptake on positron emission tomography/CT scan.

机构信息

Department of Radiology, Tri-Service General Hospital and National Defense Medical Center, Taipei 114, Taiwan, Republic of China.

出版信息

Korean J Radiol. 2013 May-Jun;14(3):540-3. doi: 10.3348/kjr.2013.14.3.540. Epub 2013 May 2.

DOI:10.3348/kjr.2013.14.3.540
PMID:23690726
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3655313/
Abstract

The radiologic appearance of multiple discrete pulmonary nodules in immunocompetent patients, with cryptococcal infection, has been rarely described. We describe a case of pulmonary cryptococcosis, presenting with bilaterally and randomly distributed nodules on a computed tomography, mimicking hematogeneous metastases. Positron emission tomography does not demonstrate 18F-fluorodeoxyglucose (FDG) uptake, suggesting a low probability for malignancy, which is a crucial piece of information for clinicians when making a management decision. We find the absence of FDG uptake correlates with the pathologic finding of an infectious nodule, composed of fibrosis and necrosis.

摘要

在免疫功能正常的患者中,新型隐球菌感染引起的多发性肺部离散结节的放射学表现很少被描述。我们描述了一例肺部隐球菌病,其计算机断层扫描表现为双侧和随机分布的结节,类似于血行转移。正电子发射断层扫描不显示 18F-氟脱氧葡萄糖(FDG)摄取,提示恶性肿瘤的可能性较低,这对于临床医生在做出治疗决策时是一个至关重要的信息。我们发现 FDG 摄取的缺失与病理发现的感染性结节相关,该结节由纤维化和坏死组成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b04/3655313/d4b5e5c7bd08/kjr-14-540-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b04/3655313/d4b5e5c7bd08/kjr-14-540-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b04/3655313/d4b5e5c7bd08/kjr-14-540-g001.jpg

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本文引用的文献

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Characteristics of integrated 18F-FDG PET/CT in Pulmonary Cryptococcosis.18F-FDG PET/CT融合显像在肺隐球菌病中的特征
Acta Radiol. 2009 May;50(4):374-8. doi: 10.1080/02841850902756532.
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