Department of Internal Medicine, St. Vincent's Hospital, The Catholic University of Korea, Suwon, South Korea.
J Interv Cardiol. 2012 Aug;25(4):330-6. doi: 10.1111/j.1540-8183.2011.00717.x. Epub 2012 Feb 26.
It is unknown whether using a single guiding catheter for both nonculprit and culprit vessel angiography and intervention during transradial primary percutaneous coronary intervention (PCI) is feasible.
This single-center study enrolled 242 consecutive patients with ST segment elevation myocardial infarction (STEMI) who received primary PCI. Among them, 102 patients received primary PCI via transfemoral approach (TFI), 109 patients received primary PCI via transradial approach using conventional technique (Conventional TRI), and 31 underwent primary TRI using a single guiding catheter (Single Guiding TRI). The catheter used for this purpose was 6 Fr RM® 3.5 guiding catheter.
Using a single guiding catheter, both coronary artery angiograms and intervention were successful in 30 of 31 patients (96.7%). Needle-to-balloon time (from puncture to first balloon) and door-to-balloon (D2B) time were similar between TFI and Conventional TRI groups and significantly lower in the Single Guiding TRI group (13.8 [TFI] and 14.1 [Conventional TRI] vs. 7.6 minutes, P < 0.001; 89.5 [TFI] and 91.0 [Conventional TRI] vs. 68.5 minutes, P = 0.008, respectively), whereas proportion of patients achieving D2B time within 90 minutes increased significantly in the Single Guiding TRI group from 51.0% for TFI and 49.5% for Conventional TRI to 74.2% (P = 0.023).
Primary transradial PCI using a single guiding catheter is feasible and highly successful and might allow timely restoration of blood flow in infarct-related artery.
经桡动脉途径行直接经皮冠状动脉介入治疗(PCI)时,使用单一指引导管对非罪犯血管和罪犯血管行造影和介入治疗是否可行尚不清楚。
本单中心研究纳入了 242 例接受直接 PCI 的 ST 段抬高型心肌梗死(STEMI)患者。其中,102 例行经股动脉途径(TFI)PCI,109 例行常规经桡动脉途径(Conventional TRI)PCI,31 例行单一指引导管经桡动脉途径(Single Guiding TRI)PCI。所用导管为 6Fr RM® 3.5 指引导管。
31 例患者中有 30 例(96.7%)成功地用单一指引导管完成了冠状动脉造影和介入治疗。TFI 组和 Conventional TRI 组的针球时间(从穿刺到第一次球囊扩张)和 door-to-balloon(D2B)时间相似,且均显著短于 Single Guiding TRI 组(13.8[TFI]和 14.1[Conventional TRI]比 7.6 分钟,P<0.001;89.5[TFI]和 91.0[Conventional TRI]比 68.5 分钟,P=0.008),而 Single Guiding TRI 组中达到 D2B 时间在 90 分钟内的患者比例从 TFI 的 51.0%和 Conventional TRI 的 49.5%显著增加到 74.2%(P=0.023)。
经单一指引导管行直接经桡动脉 PCI 是可行且高度成功的,可能可以及时恢复梗死相关动脉的血流。