Torii Sho, Fujii Toshiharu, Murakami Tsutomu, Nakazawa Gaku, Ijichi Takeshi, Nakano Masataka, Ohno Yohei, Shinozaki Norihiko, Yoshimachi Fuminobu, Ikari Yuji
Department of Cardiology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, 259-1193, Kanagawa, Japan.
Cardiovasc Interv Ther. 2017 Apr;32(2):114-119. doi: 10.1007/s12928-016-0395-z. Epub 2016 Apr 28.
The purpose of this study is to determine reduction of door-to-balloon (D2B) time using a single universal guiding catheter (Ikari-Left catheter) in transradial approach. In this procedure, we can skip a total of five steps compared with a conventional procedure (two catheter insertions, two catheter removals, and one catheter engagement). Reducing total ischemic time is important to achieving a better outcome in primary percutaneous coronary intervention (PCI) for ST segment elevation myocardial infarction (STEMI). We retrospectively compared 30 consecutive STEMI patients who underwent transradial primary PCI with a single guiding catheter (IL group) with 30 consecutive patients with conventional transradial primary PCI. Patients with cardiogenic shock, heart failure, or need for intra-aortic balloon pumping support before primary PCI were excluded. Baseline characteristics were not different between the two groups. The D2B time was significantly shorter in the IL group (55 ± 16 vs. 63 ± 17 min, respectively; p = 0.01). Puncture-to-balloon time was also significantly shorter in the IL group (15 ± 11 min vs. 25 ± 11 min, respectively; p = 0.001). The total number of diagnostic and guiding catheters was significantly less in IL group (1 (IQR 1-1) vs. 3 (IQR 3-3), respectively; p < 0.0001). Primary PCI with a single universal guiding catheter reduced D2B time by skipping several procedural steps, and reduced the total number of catheters needed. This technique could reduce patient mortality as well as total medical cost.
本研究的目的是确定在经桡动脉途径中使用单一通用引导导管(Ikari-Left导管)减少门球时间(D2B)。在此操作中,与传统操作相比,我们总共可以跳过五个步骤(两次导管插入、两次导管移除和一次导管接合)。减少总缺血时间对于在ST段抬高型心肌梗死(STEMI)的直接经皮冠状动脉介入治疗(PCI)中取得更好的结果很重要。我们回顾性比较了30例连续接受经桡动脉直接PCI并使用单一引导导管的STEMI患者(IL组)和30例连续接受传统经桡动脉直接PCI的患者。排除在直接PCI前出现心源性休克、心力衰竭或需要主动脉内球囊泵支持的患者。两组间基线特征无差异。IL组的D2B时间显著更短(分别为55±16分钟和63±17分钟;p = 0.01)。IL组的穿刺到球囊时间也显著更短(分别为15±11分钟和25±11分钟;p = 0.001)。IL组诊断和引导导管的总数显著更少(分别为1(四分位数间距1-1)和3(四分位数间距3-3);p < 0.0001)。使用单一通用引导导管进行直接PCI通过跳过几个操作步骤减少了D2B时间,并减少了所需导管的总数。该技术可以降低患者死亡率以及总医疗成本。