Lalitha Prajna, Lin Charles C, Srinivasan Muthiah, Mascarenhas Jeena, Prajna N Venkatesh, Keenan Jeremy D, McLeod Stephen D, Acharya Nisha R, Lietman Thomas M, Porco Travis C
Aravind Eye Institute, Madurai, India.
Ophthalmic Epidemiol. 2012 Apr;19(2):111-5. doi: 10.3109/09286586.2011.645990. Epub 2012 Feb 24.
In light of the increased incidence of contact lens associated Acanthamoeba keratitis in recent years, this study analyzed longitudinal trends of its incidence among predominantly non-contact lens wearers in a high-volume referral center in South India.
A retrospective analysis of microbiology laboratory records at the Aravind Eye Hospital from 1988-2009 was performed. The Maximum Excess Events Test (MEET) was used to identify epidemics of Acanthamoeba keratitis.
There were a total of 38,529 unique cases of infectious keratitis evaluated over this time period, of which 372 were culture-positive for Acanthamoeba. Only three cases (0.9%) of Acanthamoeba keratitis occurred among contact lens wearers. MEET identified unique Acanthamoeba keratitis epidemics in 1993 and 2002.
Discrete epidemics of Acanthamoeba keratitis occurred among a rural, non-contact lens wearing, population in South India in 1993 and 2002.
鉴于近年来与隐形眼镜相关的棘阿米巴角膜炎发病率上升，本研究分析了在印度南部一家大型转诊中心以非隐形眼镜佩戴者为主的人群中其发病率的纵向趋势。
对1988年至2009年阿拉文德眼科医院微生物学实验室记录进行回顾性分析。采用最大超额事件检验（MEET）来识别棘阿米巴角膜炎的流行情况。
在此期间共评估了38529例独特的感染性角膜炎病例，其中372例棘阿米巴培养呈阳性。仅3例（0.9%）棘阿米巴角膜炎发生在隐形眼镜佩戴者中。MEET识别出1993年和2002年有独特的棘阿米巴角膜炎流行。
1993年和2002年在印度南部农村非隐形眼镜佩戴人群中发生了离散的棘阿米巴角膜炎流行。
