Reiner P, Piette J-C, Leroux G, Vidailhet M, Costedoat-Chalumeau N
Service de neurologie, hôpital Lariboisière, université Paris-7, AP-HP, 75475 Paris cedex 10, France.
Rev Med Interne. 2012 Apr;33(4):206-8. doi: 10.1016/j.revmed.2012.01.006. Epub 2012 Feb 24.
Chorea may occur in patients with SLE with a frequency estimated at 1 to 3% in adults and up to 9% in paediatric lupus. Chorea is frequently a presenting feature, and is strongly related to the presence of antiphospholipid antibodies. A treatment with antiplatelet agents and hydroxychloroquine is generally sufficient. During follow-up, the patients with chorea have a significant higher risk to develop thrombotic events (mainly arterial). They also have an excess risk of obstetric morbidity and valvular disease. The prescription of antiplatelet agents and adequate management, especially during pregnancy, can probably reduce this risk.
舞蹈症可能发生在系统性红斑狼疮（SLE）患者中，据估计，其在成人中的发生率为1%至3%，在儿童狼疮患者中高达9%。舞蹈症常常是首发症状，且与抗磷脂抗体的存在密切相关。一般使用抗血小板药物和羟氯喹进行治疗就足够了。在随访期间，患有舞蹈症的患者发生血栓事件（主要是动脉血栓）的风险显著更高。他们还存在产科并发症和瓣膜病的额外风险。开具抗血小板药物并进行适当管理，尤其是在孕期，可能会降低这种风险。
