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青少年非医疗用途处方类阿片类药物使用者:简要筛查与物质使用障碍。

Adolescent nonmedical users of prescription opioids: brief screening and substance use disorders.

机构信息

Institute for Research on Women and Gender, University of Michigan-Ann Arbor, 204 S. State St., Ann Arbor, MI 48109-1290, USA.

出版信息

Addict Behav. 2012 May;37(5):651-6. doi: 10.1016/j.addbeh.2012.01.021. Epub 2012 Feb 7.

Abstract

OBJECTIVES

The objectives of this study are to examine the associations among a positive score on the CRAFFT (a substance use brief screening test for adolescents) and demographic characteristics, diversion sources, routes of administration, substance use behaviors and motivations associated with the use of prescription opioids without a legal prescription.

METHODS

In 2009-2010, a sample of 2744 middle and high school students from two Midwestern school districts in the United States self-administered a Web-based survey.

RESULTS

Approximately 5.6% (n=148) of respondents reported past-year nonmedical use of prescription opioids (NMUPO). Of those reporting NMUPO, approximately 35.1% (n=52) screened positive for substance use disorders based on the CRAFFT. Multiple logistic regression analyses indicated that the odds of buying prescription opioids, obtaining opioids from multiple diversion sources, administering opioids intranasally, and using opioids to get high were greater for nonmedical users with a positive CRAFFT screen as compared to NMUPO with a negative CRAFFT screen. NMUPO with a positive screen was motivated primarily for recreational purposes, while NMUPO with a negative screen was motivated almost exclusively by pain relief.

CONCLUSIONS

The CRAFFT brief screening test for adolescents can be used to identify a subgroup of NMUPO at the highest risk for a substance use disorder as well as a subgroup of NMUPO who would benefit from appropriate pain management.

摘要

目的

本研究旨在探讨 CRAFFT(青少年药物使用快速筛查测试)阳性评分与人口统计学特征、滥用来源、给药途径、与无合法处方使用处方类阿片相关的使用行为和动机之间的关联。

方法

2009-2010 年,美国两个中西部学区的 2744 名中学生参与了一项基于网络的自我调查。

结果

约 5.6%(n=148)的受访者报告过去一年有非医疗用途处方类阿片(NMUPO)的使用。在报告 NMUPO 的人群中,约 35.1%(n=52)根据 CRAFFT 筛查出有物质使用障碍。多变量逻辑回归分析表明,与 CRAFFT 阴性筛查的 NMUPO 相比,CRAFFT 阳性筛查的 NMUPO 更有可能通过购买处方类阿片、从多个滥用来源获取阿片类药物、经鼻给药以及使用阿片类药物来获得快感。CRAFFT 阳性筛查的 NMUPO 主要出于娱乐目的,而 CRAFFT 阴性筛查的 NMUPO 几乎完全是为了缓解疼痛。

结论

青少年 CRAFFT 简短筛查测试可用于识别 NMUPO 中具有最高物质使用障碍风险的亚组,以及需要适当疼痛管理的 NMUPO 亚组。

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