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舌骨扩张术治疗阻塞性睡眠呼吸暂停:一项初步研究。

Hyoid expansion as a treatment for obstructive sleep apnea: a pilot study.

机构信息

Department of Otorhinolaryngology, University Hospital Antwerp, Edegem, Belgium.

出版信息

Sleep Breath. 2013 Mar;17(1):195-201. doi: 10.1007/s11325-012-0673-7. Epub 2012 Feb 27.

Abstract

OBJECTIVES

Hyoid expansion is a novel procedure that was developed to widen and stabilize the lateral walls of the hypopharynx in order to improve obstructive sleep apnea. This study was conducted to evaluate the safety, efficacy and feasibility of hyoid expansion.

STUDY DESIGN

A prospective, non-randomized multicenter pilot study with a follow-up of 6 months was conducted.

METHOD

An implantable device (the Air-Frame system) was used to surgically expand the hyoid bone. Subjective and objective outcome measures were evaluated.

RESULTS

The procedure was successfully performed in all patients without technical adverse events. There were three clinical adverse events, and tolerance was good. Although there was a significant improvement in snoring and excessive daytime sleepiness, there was no objective improvement of the apnea-hypopnea index as measured by polysomnography.

CONCLUSION

Hyoid expansion did not provide objective improvement of obstructive outcome measures in patients with obstructive sleep apnea syndrome.

摘要

目的

舌骨扩张术是一种新的手术方法,旨在拓宽和稳定下咽的外侧壁,以改善阻塞性睡眠呼吸暂停。本研究旨在评估舌骨扩张术的安全性、疗效和可行性。

研究设计

一项前瞻性、非随机多中心试点研究,随访时间为 6 个月。

方法

使用可植入装置(Air-Frame 系统)进行舌骨扩张手术。评估主观和客观的结果测量指标。

结果

所有患者均成功完成手术,无技术相关不良事件。出现了 3 例临床不良事件,但耐受性良好。尽管打鼾和日间嗜睡明显改善,但多导睡眠图测量的呼吸暂停低通气指数无客观改善。

结论

舌骨扩张术并不能为阻塞性睡眠呼吸暂停综合征患者提供阻塞性结局测量指标的客观改善。

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