Hessel N S, Vries N
Department of Otorhinolaryngology, Head and Neck Surgery, Saint Lucas Andreas Hospital, Amsterdam, The Netherlands.
Clin Otolaryngol Allied Sci. 2004 Dec;29(6):682-5. doi: 10.1111/j.1365-2273.2004.00864.x.
From 70 patients who had uvulopalatopharyngoplasty (UPPP) operation and a pre- and postoperative sleep registration, we could retrospectively determine the failures and the correlation between variables such as age, gender, body mass index (BMI), earlier or concomitant tonsillectomy, unilevel (uvula-palate-tonsil) or multilevel (base of tongue as well) obstruction during sleep endoscopy and treatment outcome. From 70 patients, the preoperative sleep registration classified 15 social unacceptable snorers and 55 obstructive sleep apnoea syndrome (OSAS) patients. In this study we focused on the OSAS patients. From the 55 OSAS patients, 32 were classified as successful after UPPP, because they had a decreased apnoea-hypopnoea index (AHI) after surgery (</=20). Eight patients had a decreased AHI, but more than 20 apnoeas/hypnoeas per hour. Fifteen patients were identified as UPPP failures with an equal or increased AHI and/or subjective deterioration of snoring. We were unable to find a statistically difference between the two groups with respect to variables such as age, BMI and AHI preoperative (P > 0.56) as between the level of obstruction(s) (P > 0.24). For earlier or concomitant tonsillectomy we found a statistically difference (P > 0.039), but a very small number in the high failure group (n = 8). We conclude that although sleep endoscopy adds to better patient selection and better results, paradoxically, the finding of obstruction on palate-uvula level during sleep endoscopy can still give UPPP failures.
从70例行悬雍垂腭咽成形术(UPPP)且术前后均有睡眠记录的患者中,我们可以回顾性地确定手术失败情况以及年龄、性别、体重指数(BMI)、既往或同期扁桃体切除术、睡眠内镜检查时单平面(悬雍垂 - 腭 - 扁桃体)或多平面(舌根也包括在内)阻塞等变量与治疗结果之间的相关性。在这70例患者中,术前睡眠记录将15例社会不可接受的打鼾者和55例阻塞性睡眠呼吸暂停低通气综合征(OSAS)患者进行了分类。在本研究中,我们重点关注OSAS患者。在这55例OSAS患者中,32例在UPPP术后被归类为成功,因为他们术后的呼吸暂停低通气指数(AHI)下降(≤20)。8例患者AHI下降,但每小时仍有超过20次呼吸暂停/低通气。15例患者被确定为UPPP手术失败,其AHI相等或增加和/或打鼾主观恶化。我们未能在两组之间发现年龄、BMI和术前AHI等变量方面存在统计学差异(P>0.56),阻塞水平之间也无差异(P>0.24)。对于既往或同期扁桃体切除术,我们发现存在统计学差异(P>0.039),但高失败组中的数量非常少(n = 8)。我们得出结论,尽管睡眠内镜检查有助于更好地选择患者并取得更好的结果,但矛盾的是,睡眠内镜检查时在腭 -悬雍垂水平发现阻塞仍可能导致UPPP手术失败。