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Autologous stem cell transplant is feasible in very elderly patients with lymphoma and limited comorbidity.

作者信息

Elstrom Rebecca L, Martin Peter, Hurtado Rua Sandra, Shore Tsiporah B, Furman Richard R, Ruan Jia, Pearse Roger N, Coleman Morton, Mark Tomer, Leonard John P, Gergis Usama

出版信息

Am J Hematol. 2012 Apr;87(4):433-5. doi: 10.1002/ajh.23108. Epub 2012 Feb 24.

DOI:10.1002/ajh.23108
PMID:22367772
Abstract
摘要

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1
Autologous stem cell transplant is feasible in very elderly patients with lymphoma and limited comorbidity.自体干细胞移植对于合并症有限的老年淋巴瘤患者是可行的。
Am J Hematol. 2012 Apr;87(4):433-5. doi: 10.1002/ajh.23108. Epub 2012 Feb 24.
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Feasibility of second hematopoietic stem cell transplantation using reduced-intensity conditioning with fludarabine and melphalan after a failed autologous hematopoietic stem cell transplantation.在自体造血干细胞移植失败后，使用氟达拉滨和马法兰进行减低剂量预处理进行第二次造血干细胞移植的可行性。
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Allogeneic peripheral blood stem cell transplantation using a fludarabine-based low intensity conditioning regimen for malignant lymphoma.采用基于氟达拉滨的低强度预处理方案进行异基因外周血干细胞移植治疗恶性淋巴瘤。
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Estimating late adverse events using competing risks after autologous stem-cell transplantation in aggressive non-Hodgkin lymphoma patients.在侵袭性非霍奇金淋巴瘤患者自体干细胞移植后使用竞争风险法评估晚期不良事件。
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Outcome following Reduced-Intensity Allogeneic Stem Cell Transplantation (RIC AlloSCT) for relapsed and refractory mantle cell lymphoma (MCL): a study of the British Society for Blood and Marrow Transplantation.异基因造血干细胞移植（RIC AlloSCT）治疗复发/难治性套细胞淋巴瘤（MCL）的结局：英国血液与骨髓移植学会研究。
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Comparison of reduced-intensity and conventional myeloablative regimens for allogeneic transplantation in non-Hodgkin's lymphoma.非霍奇金淋巴瘤异基因移植中减低强度与传统清髓方案的比较。
Biol Blood Marrow Transplant. 2006 Dec;12(12):1326-34. doi: 10.1016/j.bbmt.2006.08.035.
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'Relative' chemotherapy sensitivity: the impact of number of salvage regimens prior to autologous stem cell transplant for relapsed and refractory aggressive non-Hodgkin's lymphoma.“相对”化疗敏感性：自体干细胞移植前挽救方案数量对复发难治性侵袭性非霍奇金淋巴瘤的影响
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Autologous transplantation in patients with relapsed or high-grade follicular lymphoma provides long term disease-free survival and best median duration of response.复发或高级别滤泡性淋巴瘤患者进行自体移植可实现长期无病生存，并获得最佳的中位缓解持续时间。
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Busulfan and cyclophosphamide (Bu/Cy) as a preparative regimen for autologous stem cell transplantation in patients with non-Hodgkin lymphoma: a single-institution experience.白消安和环磷酰胺（Bu/Cy）作为非霍奇金淋巴瘤患者自体干细胞移植的预处理方案：单中心经验
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Comorbidities, not age, impact outcomes in autologous stem cell transplant for relapsed non-Hodgkin lymphoma.合并症而非年龄，影响复发性非霍奇金淋巴瘤自体干细胞移植的预后。
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Cellular therapy in older adults with relapsed/refractory diffuse large B-cell lymphoma.老年复发/难治性弥漫性大B细胞淋巴瘤的细胞治疗
Front Oncol. 2024 Oct 22;14:1481950. doi: 10.3389/fonc.2024.1481950. eCollection 2024.
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Re-examining the role of hematopoietic stem cell transplantation in relapsed large B-cell lymphoma in the era of chimeric antigen receptor (CAR) T-cell therapy.重新审视造血干细胞移植在嵌合抗原受体（CAR）T细胞疗法时代复发性大B细胞淋巴瘤中的作用。
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J Pers Med. 2022 Jun 13;12(6):964. doi: 10.3390/jpm12060964.
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Outcomes of Autologous Hematopoietic Cell Transplantation in Older Patients with Diffuse Large B-Cell Lymphoma.老年弥漫性大 B 细胞淋巴瘤患者自体造血细胞移植的结果。
Transplant Cell Ther. 2022 Aug;28(8):487.e1-487.e7. doi: 10.1016/j.jtct.2022.05.029. Epub 2022 May 21.
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Toxicities of high-dose chemotherapy and autologous hematopoietic cell transplantation in older patients with lymphoma.大剂量化疗和自体造血细胞移植治疗老年淋巴瘤患者的毒性。
Blood Adv. 2021 Jun 22;5(12):2608-2618. doi: 10.1182/bloodadvances.2020004167.
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Dose-adjusted high-dose chemotherapy with autologous stem cell transplantation for elderly (≥ 70 years old) lymphoma patients.剂量调整的大剂量化疗联合自体干细胞移植治疗老年（≥70岁）淋巴瘤患者。
Ann Hematol. 2022 Jan;101(1):205-207. doi: 10.1007/s00277-020-04373-z. Epub 2021 Jan 6.
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Long-term outcomes of older patients with relapsed/refractory NHL referred to ASCT.接受自体造血干细胞移植（ASCT）的复发/难治性非霍奇金淋巴瘤（NHL）老年患者的长期预后。
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Outcome after autologous stem cell transplantation in primary refractory or relapsed Hodgkin lymphoma-a long-term follow-up single center experience.自体造血干细胞移植治疗原发性难治或复发性霍奇金淋巴瘤的疗效：单中心长期随访经验
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