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Dose-adjusted high-dose chemotherapy with autologous stem cell transplantation for elderly (≥ 70 years old) lymphoma patients.

作者信息

Hosoi Hiroki, Murata Shogo, Mushino Toshiki, Tamura Shinobu, Sonoki Takashi

机构信息

Department of Hematology/Oncology, Wakayama Medical University, Kimiidera 811-1, Wakayama, 641-8510, Japan.

出版信息

Ann Hematol. 2022 Jan;101(1):205-207. doi: 10.1007/s00277-020-04373-z. Epub 2021 Jan 6.

DOI:10.1007/s00277-020-04373-z
PMID:33404691
Abstract
摘要

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Dose-adjusted high-dose chemotherapy with autologous stem cell transplantation for elderly (≥ 70 years old) lymphoma patients.剂量调整的大剂量化疗联合自体干细胞移植治疗老年（≥70岁）淋巴瘤患者。
Ann Hematol. 2022 Jan;101(1):205-207. doi: 10.1007/s00277-020-04373-z. Epub 2021 Jan 6.
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High-dose chemotherapy with carmustine, etoposide, cytarabine and melphalan followed by autologous stem cell transplant is an effective treatment for elderly patients with poor-prognosis lymphoma.卡莫司汀、依托泊苷、阿糖胞苷和马法兰大剂量化疗后进行自体干细胞移植，是治疗预后不良的老年淋巴瘤患者的有效方法。
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[High-dose chemotherapy with autologous bone marrow transplantation: 11 years' experience in Zurich].[大剂量化疗联合自体骨髓移植：苏黎世11年经验]
Schweiz Med Wochenschr. 2000 Jan 22;130(3):60-9.
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LEAM versus CBV for conditioning in autologous hematopoietic stem cell transplantation for lymphoma.淋巴瘤自体造血干细胞移植中用于预处理的低剂量依托泊苷与环磷酰胺对比研究
Bone Marrow Transplant. 2019 Apr;54(4):625-628. doi: 10.1038/s41409-018-0349-4. Epub 2018 Oct 3.
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[The strategy of treatment for malignant lymphoma: conventional-dose chemotherapy versus high-dose therapy followed by hematopoietic stem cell transplantation].[恶性淋巴瘤的治疗策略：传统剂量化疗与大剂量治疗后造血干细胞移植]
Rinsho Ketsueki. 2004 Jan;45(1):39-47.
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High-Dose Chemotherapy and Autologous Stem Cell Transplant in Older Patients with Lymphoma.老年淋巴瘤患者的大剂量化疗与自体干细胞移植
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Hematol Oncol. 2017 Dec;35(4):576-583. doi: 10.1002/hon.2348. Epub 2016 Sep 28.
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Prognosis of patients with primary central nervous system lymphoma after high-dose chemotherapy followed by autologous stem cell transplantation.原发性中枢神经系统淋巴瘤患者在大剂量化疗后进行自体造血干细胞移植的预后。
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Intensive chemotherapy with thiotepa, busulfan and cyclophosphamide and hematopoietic stem cell rescue in relapsed or refractory primary central nervous system lymphoma and intraocular lymphoma: a retrospective study of 79 cases.在复发或难治性原发性中枢神经系统淋巴瘤和眼内淋巴瘤中采用噻替派、白消安和环磷酰胺强化化疗和造血干细胞解救：79 例回顾性研究。
Haematologica. 2012 Nov;97(11):1751-6. doi: 10.3324/haematol.2011.060434. Epub 2012 May 11.
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Reduced Intensity Conditioning Prior Autologous Stem Cell Transplantation in Elderly DLBCL Patients.老年弥漫性大B细胞淋巴瘤患者自体干细胞移植前的减低剂量预处理
Eur J Haematol. 2025 Jan;114(1):139-146. doi: 10.1111/ejh.14320. Epub 2024 Oct 9.

本文引用的文献

1
Autologous Stem Cell Transplantation in Elderly Lymphoma Patients in Their 70s: Outcomes and Analysis.自体干细胞移植在 70 多岁老年淋巴瘤患者中的应用：结果与分析。
Oncologist. 2018 May;23(5):624-630. doi: 10.1634/theoncologist.2017-0499. Epub 2017 Dec 28.
2
Toxicity and efficacy of autologous hematopoietic cell transplantation in elderly patients with aggressive lymphoma: a historical prospective study.自体造血细胞移植治疗老年侵袭性淋巴瘤的毒性与疗效：一项历史性前瞻性研究
Ann Hematol. 2018 Mar;97(3):459-466. doi: 10.1007/s00277-017-3192-6. Epub 2017 Nov 25.
3
Autologous hematopoietic stem cell transplantation in elderly patients (≥ 70 years) with non-Hodgkin's lymphoma: A French Society of Bone Marrow Transplantation and Cellular Therapy retrospective study.
老年（≥70岁）非霍奇金淋巴瘤患者的自体造血干细胞移植：法国骨髓移植与细胞治疗学会的一项回顾性研究。
J Geriatr Oncol. 2015 Sep;6(5):346-52. doi: 10.1016/j.jgo.2015.04.005. Epub 2015 Jun 23.
4
Favorable outcomes in elderly patients undergoing high-dose therapy and autologous stem cell transplantation for non-Hodgkin lymphoma.老年非霍奇金淋巴瘤患者接受大剂量治疗及自体干细胞移植的良好预后。
Biol Blood Marrow Transplant. 2014 Dec;20(12):2004-9. doi: 10.1016/j.bbmt.2014.08.019. Epub 2014 Aug 28.
5
High-dose chemotherapy with autologous stem cell transplantation for elderly patients with relapsed/refractory diffuse large B cell lymphoma: a nationwide retrospective study.老年复发/难治性弥漫性大B细胞淋巴瘤患者的大剂量化疗联合自体干细胞移植：一项全国性回顾性研究
Biol Blood Marrow Transplant. 2014 May;20(5):684-9. doi: 10.1016/j.bbmt.2014.01.025. Epub 2014 Jan 31.
6
Investigation of the freely available easy-to-use software 'EZR' for medical statistics.医学统计学中免费易用软件 EZR 的调查研究。
Bone Marrow Transplant. 2013 Mar;48(3):452-8. doi: 10.1038/bmt.2012.244. Epub 2012 Dec 3.
7
Autologous stem cell transplant is feasible in very elderly patients with lymphoma and limited comorbidity.自体干细胞移植对于合并症有限的老年淋巴瘤患者是可行的。
Am J Hematol. 2012 Apr;87(4):433-5. doi: 10.1002/ajh.23108. Epub 2012 Feb 24.
8
Outcomes of auto-SCT for lymphoma in subjects aged 70 years and over.70 岁及以上患者的淋巴瘤自体干细胞移植治疗结局。
Bone Marrow Transplant. 2011 Sep;46(9):1219-25. doi: 10.1038/bmt.2010.289. Epub 2010 Dec 13.
9
BEAM chemotherapy followed by autologous stem cell support in lymphoma patients: analysis of efficacy, toxicity and prognostic factors.淋巴瘤患者接受BEAM化疗后自体干细胞支持治疗：疗效、毒性及预后因素分析
Bone Marrow Transplant. 1997 Sep;20(6):451-8. doi: 10.1038/sj.bmt.1700913.
10
Salvage chemotherapy with mini-BEAM for relapsed or refractory non-Hodgkin's lymphoma prior to autologous bone marrow transplantation.在自体骨髓移植前，采用小剂量BEAM方案进行挽救性化疗治疗复发或难治性非霍奇金淋巴瘤。
Ann Oncol. 1997 Jul;8(7):675-80. doi: 10.1023/a:1008294725992.