胸腺五肽治疗慢性支气管炎合并细胞免疫缺陷患者疗效的临床流行病学研究
[A clinico-epidemiological study on the efficacy of thymopentin therapy in patients with chronic bronchitis and cellular immunity deficiency].
作者信息
Amoroso A, Di Rosa R, Guidotti G, Ferri G M, Afeltra A
机构信息
Clinica medica III, Università La Sapienza, Roma.
出版信息
Recenti Prog Med. 1990 Jan;81(1):29-32.
PMID:2236822
Abstract
The immunological in vivo effects of thymopentin (TP5) treatment in eleven hypo-anergic patients affected with chronic bronchitis are reported. Significant improvement of cellular immunity, evaluated by skin tests, and an increase of percentage of CD4+ cells and natural killer activity are demonstrated. The clinical evaluation showed an evident reduction of infectious episodes of acute bronchitis after TP5 treatment.
摘要
报告了胸腺五肽（TP5）治疗11例慢性支气管炎伴低反应性患者的体内免疫效应。通过皮肤试验评估，细胞免疫有显著改善，CD4 +细胞百分比和自然杀伤活性增加。临床评估显示，TP5治疗后急性支气管炎的感染发作明显减少。
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