Amoroso A, Di Rosa R, Guidotti G, Ferri G M, Afeltra A
Clinica medica III, Università La Sapienza, Roma.
Recenti Prog Med. 1990 Jan;81(1):29-32.
The immunological in vivo effects of thymopentin (TP5) treatment in eleven hypo-anergic patients affected with chronic bronchitis are reported. Significant improvement of cellular immunity, evaluated by skin tests, and an increase of percentage of CD4+ cells and natural killer activity are demonstrated. The clinical evaluation showed an evident reduction of infectious episodes of acute bronchitis after TP5 treatment.
报告了胸腺五肽(TP5)治疗11例慢性支气管炎伴低反应性患者的体内免疫效应。通过皮肤试验评估,细胞免疫有显著改善,CD4 +细胞百分比和自然杀伤活性增加。临床评估显示,TP5治疗后急性支气管炎的感染发作明显减少。