Strabismus and Paediatrics, Moorfields Eye Hospital, City Road, London, EC1V 2PD, UK.
Br J Ophthalmol. 2012 Jun;96(6):838-40. doi: 10.1136/bjophthalmol-2011-301332. Epub 2012 Feb 24.
There is considerable evidence to show that strabismus patients report their quality of life (QoL) as lower than normal controls. While the majority of patients with strabismus are treated with surgery there are a number of cases where surgery is not possible and good long-term ocular alignment can be maintained with repeated injections of botulinum toxin.
65 patients who had undergone over 25 injections of botulinum toxin A for long-term control of their deviation were identified and asked to fill in and return the Adult Strabismus questionnaire (AS-20) to assess their QoL.
46 questionnaires were available for analysis. The mean AS-20 score in our patients compared favourably with that reported for normal controls and was much higher than that reported for patients with strabismus.
Long-term injections with botulinum toxin A is a good treatment for maintaining ocular alignment if squint surgery is not indicated and those patients receiving treatment score near the level of normal controls in QoL terms.
有大量证据表明斜视患者报告的生活质量（QoL）低于正常对照组。虽然大多数斜视患者都接受手术治疗，但也有一些情况下手术不可行，通过反复注射肉毒杆菌毒素可以很好地维持长期的眼部对齐。
确定了 65 名接受超过 25 次肉毒杆菌毒素 A 注射以长期控制斜视的患者，并要求他们填写并返回成人斜视问卷（AS-20）以评估他们的 QoL。
46 份问卷可用于分析。我们患者的平均 AS-20 评分与正常对照组报告的评分相比表现良好，明显高于斜视患者的评分。
如果斜视手术不适用，长期注射肉毒杆菌毒素 A 是维持眼部对齐的一种良好治疗方法，接受治疗的患者在 QoL 方面的评分接近正常对照组的水平。
