Malhotra Ranjan, Grover Vishakha, Kapoor Anoop, Saxena Divya
Department of Periodontology and Oral Implantology, National Dental College and Hospital, Gulabgarh, Derabassi, Distt. SAS Nagar, Mohali (Punjab), India.
J Indian Soc Periodontol. 2011 Oct;15(4):349-52. doi: 10.4103/0972-124X.92567.
The key to good oral health is hidden in nature. Natural herbs like neem, tulsi, pudina, clove oil, ajwain, triphala and many more has been used since ages either as a whole single herb or as a combination against various oral health problems like bleeding gums, halitosis, mouth ulcers and preventing tooth decay. The aim of the study was to compare the efficacy of a commercially available herbal mouthrinse (Herboral) with that of chlorhexidine gluconate which is considered to be a gold standard as an anti-plaque agent.
A randomized, two-group, parallel study as a 'de novo' plaque accumulation model was carried out on 50 subjects (23 males and 27 females). At baseline, all participants received a professional prophylaxis and were randomly assigned to the test (Herbal mouthrinse) and control (Chlorhexidine Gluconate) group. On the following three days, all subjects rinsed with 10 ml of the allocated mouthrinse twice daily for 1 min. They were asked to refrain from use of any other oral hygiene measures during the study. At the end of the experimental period, plaque was assessed and a questionnaire was filled by all subjects.
Chlorhexidine (mean plaque score=1.65) inhibited plaque growth significantly more than the herbal mouthrinse (mean plaque score=1.43, P<0.001). The results of the questionnaire showed that Herboral was preferred by patients for its taste, its convenience of use and taste duration (aftertaste). However, Chlorhexidine was considered to be more effective in reducing plaque as compared to Herboral.
Herbal mouthrinse was found to be a potent plaque inhibitor, though less effective than Chlorhexidine Gluconate. However, it can serve as a good alternative for the patients with special needs as in case of diabetics, xerostomics, and so on.
良好口腔健康的关键隐藏于自然之中。自古以来，印楝、罗勒、薄荷、丁香油、阿育吠陀、三果木等天然草药就被单独使用或组合使用，以应对各种口腔健康问题，如牙龈出血、口臭、口腔溃疡和预防龋齿。本研究的目的是比较一种市售草药漱口水（Herboral）与葡萄糖酸氯己定的疗效，葡萄糖酸氯己定被认为是抗牙菌斑剂的金标准。
以“新生”菌斑积聚模型进行了一项随机、两组平行研究，研究对象为50名受试者（23名男性和27名女性）。在基线时，所有参与者都接受了专业的牙齿清洁，并被随机分配到试验组（草药漱口水）和对照组（葡萄糖酸氯己定）。在接下来的三天里，所有受试者每天用10毫升分配的漱口水漱口两次，每次1分钟。要求他们在研究期间避免使用任何其他口腔卫生措施。在实验期结束时，评估菌斑情况，并让所有受试者填写一份问卷。
氯己定（平均菌斑评分为1.65）比草药漱口水（平均菌斑评分为1.43，P<0.001）更能显著抑制菌斑生长。问卷结果显示，患者更喜欢Herboral的味道、使用便利性和味道持续时间（余味）。然而，与Herboral相比，氯己定被认为在减少菌斑方面更有效。
草药漱口水被发现是一种有效的菌斑抑制剂，尽管其效果不如葡萄糖酸氯己定。然而，它可以作为糖尿病患者、口干症患者等特殊需求患者的良好替代品。
