Naghsh Narges, Moghareabed Ahmad, Nematnejad Mahsa, Yaghini Jaber, Sadeghi Sayed Mohsen
Department of Periodontics, Dental Implants Research Center, School of Dentistry, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Endodontics, School of Dentistry, Azad Islamic University of Medical Science, Tehran, Iran.
Dent Res J (Isfahan). 2023 Jun 27;20:70. eCollection 2023.
Plant compounds such as , green tea, and chamomile have been increasingly used in recent years to achieve oral health. This study aimed to determine the antimicrobial effect of chamomile (Matrika), -green tea, and chlorhexidine (CHX) mouthwashes on some oral bacterial species.
This prospective experimental study investigated the antimicrobial properties of three mouthwashes, including chamomile (Matrika), -green tea, and CHX as well as distilled water as control on five bacterial species, including , , and as primary colonizers and and as secondary colonizers. Colony-forming unit was used to count the colonies and disc diffusion and well diffusion methods were used to measure the diameter of zone of inhibition. Data were analyzed by SPSS (version 22) software using descriptive statistics, ANOVA, Tukey, Kruskal-Wallis, and Mann-Whitney tests ( = 0.05).
CHX had a significantly higher antibacterial effect than the other two mouthwashes in all three methods ( < 0.001). Further, the herbal mouthwashes in all three methods had a statistically significant effect on the bacterial species ( < 0.001). -green tea mouthwash had a significantly higher effect than chamomile mouthwash (Matrika) on all bacterial species except for ( < 0.05).
The findings showed that herbal mouthwashes had potentially antibacterial effects, but these effects were significantly lower than that of CHX. However, more clinical studies are needed to prove the current findings.
近年来，诸如[具体植物化合物未提及]、绿茶和洋甘菊等植物化合物越来越多地被用于口腔保健。本研究旨在确定洋甘菊（母菊）、[具体植物化合物未提及]-绿茶和氯己定（CHX）漱口水对某些口腔细菌种类的抗菌作用。
这项前瞻性实验研究调查了三种漱口水的抗菌特性，包括洋甘菊（母菊）、[具体植物化合物未提及]-绿茶、CHX以及作为对照的蒸馏水对五种细菌种类的抗菌作用，其中[具体细菌种类未提及]、[具体细菌种类未提及]和[具体细菌种类未提及]作为主要定植菌，[具体细菌种类未提及]和[具体细菌种类未提及]作为次要定植菌。采用菌落形成单位来计数菌落，并使用纸片扩散法和打孔扩散法测量抑菌圈直径。使用SPSS（版本22）软件进行数据分析，采用描述性统计、方差分析、Tukey检验、Kruskal-Wallis检验和Mann-Whitney检验（α = 0.05）。
在所有三种方法中，CHX的抗菌效果均显著高于其他两种漱口水（P < 0.001）。此外，在所有三种方法中，草本漱口水对细菌种类均有统计学显著影响（P < 0.001）。除了[具体细菌种类未提及]外，[具体植物化合物未提及]-绿茶漱口水对所有细菌种类的效果均显著高于洋甘菊漱口水（母菊）（P < 0.05）。
研究结果表明，草本漱口水具有潜在的抗菌作用，但这些作用显著低于CHX。然而，需要更多的临床研究来证实当前的研究结果。
