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[冠状动脉对急性心肌梗死与血管成形术相关心绞痛的独特反应]

[Distinctive response of coronary artery compared acute myocardial infarction with angina pectoris associated with angioplasty].

作者信息

Sato T, Sato H, Tateishi H, Uchida T, Dote K

机构信息

Department of Cardiology, Hiroshima City Hospital.

出版信息

Kokyu To Junkan. 1990 Sep;38(9):887-92.

PMID:2236960
Abstract

There has been much controversy over the mechanism of successful percutaneous transluminal coronary angioplasty (PTCA). To examine clinical and angiographic factors that might be related to a successful PTCA, we assessed 224 branches treated with emergent or elective angioplasty in evolving acute myocardial infarction (AMI) and angina pectoris (AP). The patients were divided into three groups; group 1 (G1): AP (n = 113), group 2 (G2): AMI with complete obstruction of infarct-related artery (IRA) (n = 79), group 3 (G3): AMI with incomplete obstruction of IRA (n = 32). The morphology of stenotic lesion was classified into smooth type and irregular type. The former shows concentric smooth border, the latter shows eccentric irregular border and multiple irregular border according to the Ambrose classification. Regarding the severity of the stenosis immediately after successful PTCA, there was no significant differences between G2 and G3, however in G1 it was significantly higher than in other groups (G1 vs G2 vs G3, 56% vs 81% vs 78%, p less than 0.001). Irregular type at stenotic lesions before PTCA were present in 72 of 113 branches in G1 vs 60 of 69 in G2 and G3. Regarding the incidence of acute coronary obstruction during PTCA, there was no significant differences between G1 and G2. However, in G3 it was significantly higher than in other groups (G1 vs G2 vs G3, 8% vs 9% vs 38%, p less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

经皮腔内冠状动脉成形术(PTCA)成功的机制一直存在诸多争议。为了研究可能与PTCA成功相关的临床和血管造影因素,我们评估了224个在急性心肌梗死(AMI)和心绞痛(AP)进展期接受急诊或择期血管成形术治疗的分支。患者分为三组;第1组(G1):AP(n = 113),第2组(G2):梗死相关动脉(IRA)完全闭塞的AMI(n = 79),第3组(G3):IRA不完全闭塞的AMI(n = 32)。狭窄病变的形态分为光滑型和不规则型。根据安布罗斯分类,前者显示同心光滑边界,后者显示偏心不规则边界和多个不规则边界。关于成功PTCA后立即出现的狭窄严重程度,G2和G3之间无显著差异,但G1中的狭窄严重程度显著高于其他组(G1 vs G2 vs G3,56% vs 81% vs 78%,p小于0.001)。PTCA前狭窄病变为不规则型的情况,G1组113个分支中有72个,而G2组和G3组69个分支中有60个。关于PTCA期间急性冠状动脉闭塞的发生率,G1和G2之间无显著差异。然而,G3组的发生率显著高于其他组(G1 vs G2 vs G3,8% vs 9% vs 38%,p小于0.001)。(摘要截短于250字)

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