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75岁以上急性心肌梗死或不稳定型心绞痛患者的经皮腔内冠状动脉成形术

[Percutaneous transluminal coronary angioplasty in patients over 75 years old with acute myocardial infarct or unstable angina pectoris].

作者信息

Wojcik J, Chemnitius J M, Scholz K H, Ashmawy M, Kreuzer H, Tebbe U

机构信息

Abteilung Kardiologie und Pulmonologie der Georg-August-Universität Göttingen.

出版信息

Med Klin (Munich). 1990 Jul 15;85(7):409-14.

PMID:2385205
Abstract

Both increasing frequency and technical improvements of percutaneous transluminal coronary angioplasty (PTCA) have focussed attention on possible applications of PTCA in elderly patients with coronary artery disease. From January 1986 to June 1989, among 1872 patients treated with PTCA in our hospital, 42 patients (2.3%) were 75 or more years old. Of these patients, 14 presented with unstable angina, 28 patients suffered from acute myocardial infarction. PTCA was performed on stenoses of left anterior descending artery (43%), circumflex coronary artery (18%), and right coronary artery (39%), respectively. In patients with unstable angina, PTCA in 81% could reduce diameter stenoses of culprit lesions to 50% or less. 43% of patients with acute myocardial infarction had received previous thrombolytic therapy with streptokinase or urokinase applied either systemically or intracoronarily. On cardiac catheterization, 39% of patients presenting with acute myocardial infarction showed total occlusion of the infarct-related vessel. In 75% of patients with acute myocardial infarction, after PTCA, patency of the infarct-related artery (diameter stenoses 50% or less) was observed. In-hospital mortality of patients with acute myocardial infarction subjected to PTCA was 10%, two patients dying in prolonged cardiogenic shock, one in septic shock. In 20% of cases, coronary dissection was observed after PTCA. Non-Q-wave infarction developed in one patient. Three patients had a peripheral vascular complication, and in one patient a transient ischemic attack was observed. No severe catheter-related complications occurred after thrombolytic therapy.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

经皮腔内冠状动脉成形术(PTCA)频率的增加和技术的改进都使人们将注意力集中在PTCA在老年冠状动脉疾病患者中的可能应用上。1986年1月至1989年6月,在我院接受PTCA治疗的1872例患者中,42例(2.3%)年龄在75岁及以上。这些患者中,14例表现为不稳定型心绞痛,28例患有急性心肌梗死。PTCA分别针对左前降支(43%)、回旋支冠状动脉(18%)和右冠状动脉(39%)的狭窄进行。在不稳定型心绞痛患者中,81%的PTCA可将罪犯病变的直径狭窄降至50%或更低。43%的急性心肌梗死患者此前接受过链激酶或尿激酶全身或冠状动脉内溶栓治疗。在心脏导管检查中,39%的急性心肌梗死患者显示梗死相关血管完全闭塞。在75%的急性心肌梗死患者中,PTCA后观察到梗死相关动脉通畅(直径狭窄50%或更低)。接受PTCA的急性心肌梗死患者的院内死亡率为10%,2例死于长时间的心源性休克,1例死于感染性休克。在20%的病例中,PTCA后观察到冠状动脉夹层。1例患者发生非Q波梗死。3例患者出现周围血管并发症,1例患者观察到短暂性脑缺血发作。溶栓治疗后未发生严重的导管相关并发症。(摘要截短至250字)

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