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[成人法洛四联症合并明显左心室功能障碍的成功手术病例]

[A successfully operated case of tetralogy of Fallot with marked left ventricular dysfunction in adult].

作者信息

Itoh A, Okubo S, Nakanishi N, Yoshioka T, Kunieda T, Kawazoe K, Kito Y

机构信息

Division of Cardiology, National Cardiovascular Center.

出版信息

Kokyu To Junkan. 1990 Sep;38(9):909-12.

PMID:2236964
Abstract

Adults, especially high-aged patients with tetralogy of Fallot (TOF) are said to have a higher operative risk than younger ones because of fragility of their myocardium, bleeding from rich collateral circulation to lungs, and other complications such as brain abscess and endocarditis. It is often difficult to determine the surgical risk for total correction in cases of high-aged patients who have such complications. We report a successfully operated high-aged case of TOF with marked left ventricular dysfunction. A 52-year-old male was referred to our hospital because of exertional dyspnea and cyanosis. He had a history of cerebral embolism and meningitis several months prior to admission. On admission, he was NYHA class 3, and cyanosis and clubbed fingers were present. Cardiac catheterization showed a large VSD, 50% over-riding of the aorta and an infundibular pulmonary stenosis. Right to left shunt was 60% and Qp/Qs was 0.38. The left ventricular end diastolic volume index was 109 ml/m2, slightly larger than normal, and the ejection fraction was only 30%. This left ventricular dysfunction was thought to be caused by fibrosis of the myocardium due to longstanding hypoxemia and hypoxemia itself. There is no previous case report dealing with a successful total correction for a high-aged patient with TOF associated with such a severe left ventricular dysfunction. Congestive heart failure in the post-operative period was successfully treated by catecholamine for two weeks. Postoperative cardiac catheterization showed a small left-to-right shunt, and an improvement of left ventricular ejection fraction from 30% to 38%.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

成人,尤其是高龄法洛四联症(TOF)患者,据说由于其心肌脆弱、肺部丰富侧支循环出血以及脑脓肿和心内膜炎等其他并发症,手术风险高于年轻患者。对于有此类并发症的高龄患者,往往难以确定完全矫正的手术风险。我们报告一例成功手术的高龄TOF病例,该患者伴有明显的左心室功能障碍。一名52岁男性因劳力性呼吸困难和发绀转诊至我院。入院前数月他有脑栓塞和脑膜炎病史。入院时,他为纽约心脏协会(NYHA)心功能3级,存在发绀和杵状指。心导管检查显示有大型室间隔缺损、主动脉骑跨50%以及漏斗部肺动脉狭窄。右向左分流为60%,肺循环血流量/体循环血流量(Qp/Qs)为0.38。左心室舒张末期容积指数为109 ml/m²,略大于正常,射血分数仅为30%。这种左心室功能障碍被认为是由于长期低氧血症导致的心肌纤维化以及低氧血症本身所致。此前尚无关于伴有如此严重左心室功能障碍的高龄TOF患者成功完全矫正的病例报告。术后充血性心力衰竭通过使用儿茶酚胺成功治疗了两周。术后心导管检查显示有小的左向右分流,左心室射血分数从30%提高到了38%。(摘要截断于250字)

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