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法洛四联症修复术后左心室容积特征及其与右心室的关系

[Left ventricular volume characteristics and its relationship with right ventricle after repair of tetralogy of Fallot].

作者信息

Kobayashi J, Nakano S, Matsuda H, Shimazaki Y, Tokuan Y, Kawashima Y

出版信息

Kokyu To Junkan. 1989 Sep;37(9):983-9.

PMID:2595141
Abstract

In order to study the left ventricular volume characteristics and right ventricular influence on left ventricle, cardiac catheterization and biplane cineangiography was performed in 61 patients after repair of tetralogy of Fallot. Preoperative left ventricular volume size was also measured in 25 patients. Postoperative left ventricular end-diastolic volume index (LVEDVI) was 93 +/- 22 ml/m2 (mean +/- standard deviation) and it was 140 +/- 29% of normal left ventricular volume. Left ventricular ejection fraction (LVEF) was 60 +/- 6%. Left ventricular size significantly increased from 109 +/- 25% to 140 +/- 23% of normal by corrective surgery (p less than 0.001). Left ventricular volume characteristics are correlated with right ventricle. LVEDVI increased with increasing right ventricular end-diastolic volume index (RVEDVI) and decreased right ventricular ejection fraction (RVEF). LVEDVI (ml/m2) = 60 + 0.29 RVEDVI (ml/m2), r = 0.52, p less than 0.001, LVEDVI (ml/m2) = 141 - 0.90 RVEF (%), r = -0.30, p less than 0.02. LVEF decreased with increasing RVEDVI and decreased RVEF. LVEF (%) = 68 - 0.075 RVEDVI (ml/m2), r = -0.51, p less than 0.001, LVEF (%) = 43 + 0.32 RVEF (%), r = 0.40, p less than 0.001. On the contrary there was no relationship between right ventricular volume characteristics and right ventricular systolic pressure. There were two cases whose LVEF was less than 50%. In one case right ventricular systolic pressure was as high as 98 mmHg. In the other patient RVEDVI was 299 ml/m2 (453% of normal right ventricular volume) because of severe pulmonary regurgitation.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为研究法洛四联症修复术后患者的左心室容积特征及右心室对左心室的影响,对61例患者进行了心导管检查和双平面心血管造影。同时对25例患者术前的左心室容积大小进行了测量。术后左心室舒张末期容积指数(LVEDVI)为93±22ml/m²(均值±标准差),为正常左心室容积的140±29%。左心室射血分数(LVEF)为60±6%。通过矫正手术,左心室大小从正常的109±25%显著增加至140±23%(p<0.001)。左心室容积特征与右心室相关。LVEDVI随右心室舒张末期容积指数(RVEDVI)增加而升高,随右心室射血分数(RVEF)降低而降低。LVEDVI(ml/m²)=60 + 0.29 RVEDVI(ml/m²),r = 0.52,p<0.001,LVEDVI(ml/m²)=141 - 0.90 RVEF(%),r = -0.30,p<0.02。LVEF随RVEDVI增加及RVEF降低而降低。LVEF(%)=68 - 0.075 RVEDVI(ml/m²),r = -0.51,p<0.001,LVEF(%)=43 + 0.32 RVEF(%),r = 0.40,p<0.001。相反,右心室容积特征与右心室收缩压之间无相关性。有2例患者LVEF低于50%。1例患者右心室收缩压高达98mmHg。另1例患者因严重肺反流,RVEDVI为299ml/m²(为正常右心室容积的453%)。(摘要截选至250词)

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