Punzo Bravo G, Corona Vázquez T, Morales Polanco M, Godínez Quezada R, Estañol Vidal B
Del Servicio de Neurología, Hospital de Especialidades, Centro Médico Nacional, México, D.F.
Rev Invest Clin. 1990 Jan-Mar;42(1):23-8.
We studied in twenty patients with proven cerebral cysticercosis the presence of plasma cells in the cerebrospinal fluid (CSF). We found plasma cells in 50 per cent of the patients. All of them had subarachnoid cysticercosis or basal arachnoiditis. The presence of plasma cells was significantly associated to higher protein levels, greater number of inflammatory cells, and higher levels of IgG in the CSF. None of the patients had received medical treatment or steroids prior to the test. These findings suggest a role of plasma cells in the pathogenesis of the cysticercotic disease. The presence of plasma cells in the CSF is part of the immune response against the parasite. We also found that plasma cells are more frequently encountered in the CSF (50 per cent) than eosinophils (20 per cent) in patients with cerebral cysticercosis.
我们在20例已确诊为脑囊尾蚴病的患者中研究了脑脊液(CSF)中浆细胞的存在情况。我们在50%的患者中发现了浆细胞。所有这些患者均患有蛛网膜下腔囊尾蚴病或基底蛛网膜膜炎。浆细胞的存在与脑脊液中较高的蛋白质水平、较多的炎性细胞数量以及较高的IgG水平显著相关。在检测前,所有患者均未接受过药物治疗或类固醇治疗。这些发现提示浆细胞在囊尾蚴病发病机制中发挥作用。脑脊液中浆细胞的存在是针对寄生虫的免疫反应的一部分。我们还发现,在脑囊尾蚴病患者中,脑脊液中浆细胞的出现频率(50%)高于嗜酸性粒细胞(20%)。