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五例脑囊尾蚴病患者的脑脊液细胞学检查

Cerebrospinal fluid cytology in five patients with cerebral cysticercosis.

作者信息

Wilber R R, King E B, Howes E L

出版信息

Acta Cytol. 1980 Sep-Oct;24(5):421-6.

PMID:6933803
Abstract

Cerebral cysticercosis from Taenia solium infection is a common disease in Central American countries but an infrequent one in the United States. We report distinctive cellular findings in cerebrospinal fluid (CSF) and attendant clinical features in five patients from Central America. The patients' histories showed variable previous parasitic infestations; their neurologic symptoms and signs usually were nonfocal. Routine examination of CSF of the five patients revealed elevated leukocyte counts, but eosinophilia was found in only two. Three of the CSFs showed marked pleocytosis, high variability and atypia, indicating possible lymphoma of the central nervous system. No hooklets or other structures associated with parasitic invasion were identified. The clinical findings, together with the cellular pleomorphism in CSF, generally suggested an inflammatory lesion rather than lymphoma. In cerebral cysticercosis, confirmation of diagnosis requires proof of the etiologic agent.

摘要

由猪带绦虫感染引起的脑囊尾蚴病在中美洲国家是一种常见疾病,但在美国并不常见。我们报告了来自中美洲的5例患者脑脊液(CSF)中独特的细胞检查结果及相关临床特征。患者既往有不同的寄生虫感染史;其神经症状和体征通常无局灶性。对这5例患者的脑脊液进行常规检查发现白细胞计数升高,但仅2例有嗜酸性粒细胞增多。其中3例脑脊液显示明显的细胞增多、高度变异性和异型性,提示可能为中枢神经系统淋巴瘤。未发现与寄生虫侵袭相关的小钩或其他结构。临床发现以及脑脊液中的细胞多形性,总体提示为炎症性病变而非淋巴瘤。在脑囊尾蚴病中,确诊需要找到病原体。

相似文献

1
Cerebrospinal fluid cytology in five patients with cerebral cysticercosis.五例脑囊尾蚴病患者的脑脊液细胞学检查
Acta Cytol. 1980 Sep-Oct;24(5):421-6.
2
[Cerebral cysticercosis value of examination of eosinophilic granulocytes in CSF].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1991 Jun;13(3):224-6.
3
Diagnostic significance of eosinophilia of the cerebrospinal fluid in cerebral cysticercosis.脑脊液嗜酸性粒细胞增多在脑囊尾蚴病中的诊断意义。
Chin Med J (Engl). 1993 Apr;106(4):282-4.
4
[Plasma cells in the cerebrospinal fluid of patients with cerebral cysticercosis].[脑囊尾蚴病患者脑脊液中的浆细胞]
Rev Invest Clin. 1990 Jan-Mar;42(1):23-8.
5
[Cerebrospinal fluid in cysticercosis of the brain].
Arq Neuropsiquiatr. 1979 Jun;37(2):113-26.
6
[Examination of eosinophilic white cells in the cerebrospinal fluid and its clinical significance].[脑脊液中嗜酸性白细胞的检测及其临床意义]
Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1984 Aug;17(4):226-7.
7
Cerebral cysticercosis.脑囊尾蚴病
Pediatrics. 1979 May;63(5):761-3.
8
[Acute meningitis with cerebrospinal fluid eosinophilia: neurocysticercosis].
Psychiatr Neurol Med Psychol (Leipz). 1989 Sep;41(9):545-9.
9
[Comparative study of cerebrospinal fluid and blood in syphilis and cerebral cysticercosis].[梅毒与脑囊尾蚴病患者脑脊液与血液的对比研究]
Neurocirugia. 1969 Jan-Sep;27(1):61-8.
10
[Clinical characteristics and therapy of neurosyphilis in patients who are negative for human immunodeficiency virus].人类免疫缺陷病毒阴性患者神经梅毒的临床特征与治疗
Srp Arh Celok Lek. 1999 Jul-Aug;127(7-8):236-40.

引用本文的文献

1
Intraventricular neurocysticercosis.脑室内神经囊尾蚴病
Indian J Pediatr. 2009 Apr;76(4):420-3. doi: 10.1007/s12098-009-0023-3. Epub 2009 Feb 10.
2
Acute cysticercal meningitis--missed diagnosis.急性囊尾蚴性脑膜炎——漏诊
Indian J Pediatr. 2006 Sep;73(9):835-7. doi: 10.1007/BF02790397.
3
Multilevel intramedullary spinal neurocysticercosis with eosinophilic meningitis.伴有嗜酸性脑膜炎的多级脊髓内神经囊尾蚴病
Arch Neurol. 2004 May;61(5):770-2. doi: 10.1001/archneur.61.5.770.