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对肝切除手术患者发病率和死亡率的有效影响因素的前瞻性评估。

Prospective evaluation of the factors effective on morbidity and mortality of the patients having liver resection surgeries.

作者信息

Yildirim Ilknur Ozdogan, Salihoglu Ziya, Bolayirli Murat I, Colakoglu Nilgun, Yuceyar Lale

机构信息

Anesthesiology and Reanimation Department, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.

出版信息

Hepatogastroenterology. 2012 Sep;59(118):1928-32. doi: 10.5754/hge11660.

DOI:10.5754/hge11660
PMID:22369741
Abstract

BACKGROUND/AIMS: The objective of this study is to evaluate the factors effective on mortality and morbidity of the patients operated for liver tumor.

METHODOLOGY

Thirty-four patients who were operated for liver tumor between January 1st 2008 and December 31st 2009 in Cerrahpasa Medical Faculty have been included in this study. Patient preoperative, perioperative and postoperative characteristics and the effects of these characteristics on mortality, morbidity and the length of hospital stay were evaluated.

RESULTS

Most common postoperative complications during the study were fever and surgical site infection. Nineteen of the patients with blood loss over 1, 000 mL had the need for postoperative ICU treatment. The presence of concomitant disease, especially diabetes mellitus, liver disease and cardiovascular diseases and more than 2 units transfusion of erythrocyte suspension and fresh frozen plasma were considered related to mortality and morbidity.

CONCLUSIONS

Patient preoperative, perioperative and postoperative characteristics affect patient morbidity and mortality in liver resection surgery. Diagnosing liver tumors early and thus reducing surgical site blood loss and use of blood products will decrease mortality and morbidity ratios after liver surgeries.

摘要

背景/目的:本研究的目的是评估对肝肿瘤手术患者死亡率和发病率有影响的因素。

方法

本研究纳入了2008年1月1日至2009年12月31日在切拉帕夏医学院接受肝肿瘤手术的34例患者。评估了患者术前、围手术期和术后的特征以及这些特征对死亡率、发病率和住院时间的影响。

结果

研究期间最常见的术后并发症是发热和手术部位感染。失血超过1000毫升的患者中有19例需要术后重症监护治疗。合并疾病的存在,尤其是糖尿病、肝病和心血管疾病以及超过2单位红细胞悬液和新鲜冰冻血浆的输注被认为与死亡率和发病率有关。

结论

患者术前、围手术期和术后的特征影响肝切除手术患者的发病率和死亡率。早期诊断肝肿瘤,从而减少手术部位失血和血液制品的使用,将降低肝脏手术后的死亡率和发病率。

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Prospective evaluation of the factors effective on morbidity and mortality of the patients having liver resection surgeries.对肝切除手术患者发病率和死亡率的有效影响因素的前瞻性评估。
Hepatogastroenterology. 2012 Sep;59(118):1928-32. doi: 10.5754/hge11660.
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Transfusion criteria for fresh frozen plasma in liver resection: a 3 + 3 cohort expansion study.肝切除术中新鲜冰冻血浆的输血标准:一项3+3队列扩展研究。
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Getting started as a hepatobiliary surgeon: lessons learned from the first 100 hepatectomies as a consultant.成为一名肝胆外科医生的起步:作为顾问医生完成首例100例肝切除术后的经验教训。
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