Tan Kai, DU Xilin, Yin Jikai, Dong Rui, Zang Li, Yang Tao, Chen Yafeng
Department of General Surgery, Second Division, TangDu Hospital Affiliated to the Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
Biomed Rep. 2014 Mar;2(2):177-182. doi: 10.3892/br.2014.227. Epub 2014 Jan 20.
Anatomical liver resection is currently the preferred treatment for liver cancer. With the recent introduction of medical microwave coagulation for liver metastases, anatomical hepatectomy may be performed more efficiently. The present study retrospectively reviewed the results of microwave tissue coagulation performed during anatomical liver resection for patients with liver disease at the TangDu Hospital (Xi'an, China) between January, 2009 and June, 2012. A total of 128 patients met the inclusion criteria and were divided into two groups for comparison; those treated with the microwave coagulation technique (n=66) and the conventional group (n=62), who were treated with standard partial hepatectomy. There was no reported perioperative mortality. The univariate analysis revealed that the duration of liver dissection, intraoperative blood loss, intraoperative erythrocyte transfusion volume and alanine aminotransferase levels on the 5th postoperative day were significantly different between the microwave and conventional groups (P<0.05). Therefore, microwave tissue coagulation in anatomical liver resection was shown to be efficacious and safe and, provided proficient skills are developed in this technique, microwave tissue coagulation may be an effective alternative to anatomical hepatectomy.
解剖性肝切除术是目前肝癌的首选治疗方法。随着近期医学微波凝固技术用于肝转移瘤的治疗，解剖性肝切除术可能会更高效地实施。本研究回顾性分析了2009年1月至2012年6月期间在中国西安唐都医院对肝病患者行解剖性肝切除术中进行微波组织凝固的结果。共有128例患者符合纳入标准并分为两组进行比较，即接受微波凝固技术治疗的患者（n = 66）和接受标准肝部分切除术治疗的传统组（n = 62）。未报告围手术期死亡情况。单因素分析显示，微波组与传统组之间在肝切除时间、术中失血量、术中红细胞输注量以及术后第5天的丙氨酸转氨酶水平方面存在显著差异（P < 0.05）。因此，解剖性肝切除术中的微波组织凝固被证明是有效且安全的，并且如果在该技术方面培养出熟练的技能，微波组织凝固可能是解剖性肝切除术的一种有效替代方法。
