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急性冠状动脉综合征。挑战心肌梗死后公认的血清钾目标。

Acute coronary syndromes. Challenging accepted post-MI serum potassium targets.

机构信息

Duke Clinical Research Institute, Duke University Medical Center, 2400 Pratt Street, Durham, NC 27705, USA.

出版信息

Nat Rev Cardiol. 2012 Feb 28;9(5):259-60. doi: 10.1038/nrcardio.2012.28.

DOI:10.1038/nrcardio.2012.28
PMID:22371108
Abstract

On the basis of high-quality observational data, Goyal et al. have found that serum potassium levels <3.5 mmol/l or ≥4.5 mmol/l are associated with increased in-hospital mortality in patients with acute myocardial infarction. We discuss whether target potassium levels in clinical practice and guidelines should be changed to 3.5–4.5 mmol/l.

摘要

基于高质量的观察性数据，Goyal 等人发现血清钾水平 <3.5mmol/l 或 ≥4.5mmol/l 与急性心肌梗死患者住院死亡率增加相关。我们讨论了在临床实践和指南中是否应该将目标钾水平改为 3.5-4.5mmol/l。

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本文引用的文献

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Circulation. 2004 Aug 3;110(5):588-636. doi: 10.1161/01.CIR.0000134791.68010.FA.
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What is the optimal serum potassium level in cardiovascular patients?心血管疾病患者的最佳血清钾水平是多少？
J Am Coll Cardiol. 2004 Jan 21;43(2):155-61. doi: 10.1016/j.jacc.2003.06.021.
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Early administration of intravenous magnesium to high-risk patients with acute myocardial infarction in the Magnesium in Coronaries (MAGIC) Trial: a randomised controlled trial.冠状动脉疾病镁治疗（MAGIC）试验中，对急性心肌梗死高危患者早期静脉注射镁：一项随机对照试验。
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6
New guidelines for potassium replacement in clinical practice: a contemporary review by the National Council on Potassium in Clinical Practice.临床实践中钾补充的新指南：临床实践中钾问题全国委员会的当代综述
Arch Intern Med. 2000 Sep 11;160(16):2429-36. doi: 10.1001/archinte.160.16.2429.
7
Importance of potassium in patients with acute myocardial infarction.钾在急性心肌梗死患者中的重要性。
Acta Med Scand Suppl. 1981;647:87-93. doi: 10.1111/j.0954-6820.1981.tb02643.x.
8
Hypokalemia from beta2-receptor stimulation by circulating epinephrine.循环肾上腺素通过β2受体刺激导致低钾血症。
N Engl J Med. 1983 Dec 8;309(23):1414-9. doi: 10.1056/NEJM198312083092303.
9
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Arch Intern Med. 1987 Mar;147(3):465-9.
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