Tellez A, Perez-Breña P, Fernandez-Patiño M V, León P, Anda P, Nájera R
Centro Nacional de Microbiología, Virología e Inmunología Sanitarias, Instituto de Salud Carlos III, Madrid, Spain.
Rev Infect Dis. 1990 Sep-Oct;12(5):745-53. doi: 10.1093/clinids/12.5.745.
The clinical and epidemiologic features of viral and nonviral pathogens involved in acute respiratory diseases are described in the context of cases of infection (especially atypical pneumonia and bronchiolitis) studied at the Centro Nacional de Microbiología, Virología e Immunología Sanitarias in Madrid during a 7-year period (1979-1986). These etiologies were demonstrated in 1,637 (36.2%) of 4,521 cases. Among viruses, respiratory syncytial virus most frequently infected children; influenza virus showed the same pattern of circulation as in other European countries. Of nonviral agents, Mycoplasma pneumoniae and C. burnetii were most often involved in lower respiratory tract infections, with a variable predominance in patients of different ages. A high proportion of cases of M. pneumoniae infection occurred in infants and children aged less than 1 year, and most of these cases occurred during spring and summer. The majority of Q fever cases, including those observed in two outbreaks, occurred in the northern region.
马德里国家卫生微生物学、病毒学和免疫学中心在1979年至1986年的7年期间，对感染病例（尤其是非典型肺炎和细支气管炎）进行了研究，描述了涉及急性呼吸道疾病的病毒和非病毒病原体的临床和流行病学特征。在4521例病例中，有1637例（36.2%）证实了这些病因。在病毒中，呼吸道合胞病毒最常感染儿童；流感病毒的传播模式与其他欧洲国家相同。在非病毒病原体中，肺炎支原体和伯纳特柯克斯体最常累及下呼吸道感染，在不同年龄段的患者中优势各异。肺炎支原体感染的很大一部分病例发生在1岁以下的婴儿和儿童中，其中大多数病例发生在春季和夏季。大多数Q热病例，包括在两次疫情中观察到的病例，发生在北部地区。
