Department of Medicine, Sungkyunkwan University School of Medicine, Gangnam-gu, Seoul, Korea.
Radiology. 2012 May;263(2):562-8. doi: 10.1148/radiol.11111463. Epub 2012 Feb 27.
To evaluate whether air pockets (tracheobronchial air columns in the space between the outer surface of the stent and the adjacent airway wall) discernible at computed tomography (CT) can help optimize the time of stent removal in patients with posttuberculosis tracheobronchial stenosis (PTTS).
The study was approved by the institutional review board, and informed consent was obtained from all patients. Data from 41 patients (five men, 36 women) with a median age of 39 years (range, 21-64 years) who underwent silicone stent placement owing to PTTS, followed by CT and stent removal 6-12 months after clinical stabilization, were investigated retrospectively. Two radiologists determined whether the extent of air pockets on CT scans was associated with clinical success, which was defined as maintenance of a prosthesis-free airway for more than 2 years after stent removal. Radiologic features were compared for outcome by using a Wilcoxon two-sample test or Fisher exact test.
Stents were removed successfully in 31 patients (76%). Air pockets longer than 1 cm or longer than 2 cm were associated with successful stent removal (P = .04 and P = .006, respectively). The sensitivity and specificity of air pocket length in the prediction of successful stent removal were 84% and 50%, respectively, for air pockets longer than 1 cm and 68% and 70% for air pockets longer than 2 cm.
The extent of air pockets at chest CT shows correlation with the success of stent removal, indicates regression of stenosis, and may help guide the optimal time for stent removal.
评估计算机断层扫描(CT)中是否可见气腔(支架外表面与相邻气道壁之间的气管支气管空气柱)是否有助于优化肺结核后气管支气管狭窄(PTTS)患者支架取出的时间。
本研究经机构审查委员会批准,并获得所有患者的知情同意。回顾性分析了 41 例因 PTTS 接受硅胶支架置入、6-12 个月后临床稳定行 CT 检查和支架取出的患者(5 例男性,36 例女性;中位年龄 39 岁,范围 21-64 岁)的数据。两位放射科医生确定 CT 扫描上气腔的范围是否与临床成功相关,临床成功定义为支架取出后 2 年以上保持无假体气道。采用 Wilcoxon 两样本检验或 Fisher 确切概率法比较不同结果的影像学特征。
31 例(76%)患者成功取出支架。气腔长度超过 1cm 或超过 2cm 与成功取出支架相关(P =.04 和 P =.006)。气腔长度大于 1cm 预测支架取出成功的灵敏度和特异性分别为 84%和 50%,气腔长度大于 2cm 分别为 68%和 70%。
胸部 CT 上气腔的范围与支架取出的成功相关,表明狭窄的消退,可能有助于指导支架取出的最佳时间。