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气管切开术后气管狭窄类型鉴别诊断的临床意义

Clinical implications of differentiating between types of post-tracheostomy tracheal stenosis.

作者信息

Shin Beomsu, Kim Kang, Jeong Byeong-Ho, Eom Jung Seop, Song Won Jun, Kim Hojoong

机构信息

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Department of Internal Medicine, Pusan National University School of Medicine, Busan, South Korea.

出版信息

J Thorac Dis. 2017 Nov;9(11):4413-4423. doi: 10.21037/jtd.2017.10.99.

Abstract

BACKGROUND

Post-tracheostomy tracheal stenosis (PTTS) can be divided into four types according to stenosis mechanism and site: subglottic, stoma, cuff, and tip granuloma. However, there is little information available regarding clinical differences among types of PTTS; therefore, we evaluated the clinical differences between these types.

METHODS

We retrospectively evaluated 99 PTTS patients who underwent interventional bronchoscopy between 2004 and 2014. Patients were divided into two groups according to pathophysiological similarities as follows: subglottic or stoma type (n=59) and cuff or tip type (n=40).

RESULTS

There were no differences in baseline characteristics between groups. However, silicone stents were more frequently needed in patients with subglottic or stoma type stenosis (76%) than those with cuff or tip type stenosis (55%, P=0.031) to maintain airway patency. On the contrary, permanent tracheostomy was more frequently performed in patients with cuff or tip type stenosis (50%) than those with subglottic or stoma type stenosis (19%, P=0.002). Finally, successful removal of the tracheostomy tube without surgery and procedure- or disease-related mortality were more frequently achieved in patients with subglottic or stoma type stenosis (71%) than those with cuff or tip type stenosis (45%, P=0.012).

CONCLUSIONS

Although there were no significant differences in baseline characteristics between PTTS types, patients with subglottic or stoma type stenosis had more favorable outcomes than those with cuff or tip type stenosis. Therefore, it could be important to distinguish between types of PTTS when assessing prognosis.

摘要

背景

气管切开术后气管狭窄(PTTS)可根据狭窄机制和部位分为四种类型:声门下型、造口型、套囊型和尖端肉芽肿型。然而,关于PTTS各类型之间的临床差异,目前可用信息较少;因此,我们评估了这些类型之间的临床差异。

方法

我们回顾性评估了2004年至2014年间接受介入性支气管镜检查的99例PTTS患者。根据病理生理相似性将患者分为两组:声门下型或造口型(n = 59)和套囊型或尖端型(n = 40)。

结果

两组之间的基线特征无差异。然而,为维持气道通畅,声门下型或造口型狭窄患者(76%)比套囊型或尖端型狭窄患者(55%,P = 0.031)更频繁地需要使用硅酮支架。相反,套囊型或尖端型狭窄患者(50%)比声门下型或造口型狭窄患者(19%,P = 0.002)更频繁地进行永久性气管切开术。最后,声门下型或造口型狭窄患者(71%)比套囊型或尖端型狭窄患者(45%,P = 0.012)更频繁地在无手术的情况下成功拔除气管切开管,且手术或疾病相关死亡率更低。

结论

虽然PTTS各类型之间的基线特征无显著差异,但声门下型或造口型狭窄患者的预后比套囊型或尖端型狭窄患者更好。因此,在评估预后时区分PTTS的类型可能很重要。

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