Department of Pediatric Cardiology and General Pediatrics, Medical University of Warsaw, Warsaw, Poland.
Arch Med Sci. 2010 Aug 30;6(4):567-72. doi: 10.5114/aoms.2010.14469. Epub 2010 Sep 7.
The aim of this study was to evaluate the right atrial (RA) and right ventricular (RV) size, and the speed of their normalization, in children after percutaneous closure of secundum atrial septal defect with the Amplatzer septal occluder.
The study group consisted of 42 children, aged 4.5 to 18.5 years. The following measurements (indexed to body surface area) were performed using 2D echocardiography: longitudinal, transverse axis and area of RA, RV inflow dimensions at one-third, and halfway between the tricuspid annulus and the apex (in the apical 4-chamber view), short axis and M-mode RV diastolic dimensions. All measurements were obtained 24 h and 1, 3 and 12 months after the procedure, then annually over 4 years of follow-up, and compared with the values obtained from the control groups.
A significant decrease in all RA and RV values was observed after 24 h. Right ventricular transverse dimension normalized after 1 month, the RA longitudinal axis and area and the RV inflow dimensions after 3 months, and the RA transverse axis and M-mode RV diastolic dimension after 2 years, but the ratio of transverse to longitudinal RA axis remained significantly higher.
Right atrial and right ventricular measurements decrease rapidly during the first 24 h, and most of them normalize within a 3-month period. M-mode RV diastolic dimension does not capture the real RV changes. Amplatzer septal occluder closure of ASD influences the RA geometry, which is reflected by the higher transverse to longitudinal RA axis ratio.
本研究旨在评估儿童经皮房间隔缺损封堵术(Amplatzer 房间隔封堵器)后右心房(RA)和右心室(RV)的大小及其正常化速度。
研究组包括 42 名年龄为 4.5 至 18.5 岁的儿童。使用二维超声心动图测量以下指标(以体表面积为指标):RA 的纵向、横向轴和面积,RV 流入道在三尖瓣环和心尖之间的三分之一和一半处的尺寸(在心尖四腔视图中),短轴和 M 型 RV 舒张期尺寸。所有测量均在术后 24 小时和 1、3 和 12 个月以及 4 年随访期间每年进行,并与对照组的测量值进行比较。
术后 24 小时所有 RA 和 RV 值均显著下降。RV 横向尺寸在 1 个月后正常化,RA 纵向轴和面积以及 RV 流入道尺寸在 3 个月后正常化,RA 横向轴和 M 型 RV 舒张期尺寸在 2 年后正常化,但 RA 横向轴与纵向轴的比值仍显著较高。
右心房和右心室测量值在术后 24 小时内迅速下降,其中大部分在 3 个月内恢复正常。M 型 RV 舒张期尺寸不能反映真实的 RV 变化。ASD 的 Amplatzer 房间隔封堵器关闭会影响 RA 几何形状,这反映在 RA 横向轴与纵向轴的比值较高。