Vento Seija, Virkkula Paula
Helsingin Yliopistollinen keskussairaala, korva-, nenä- ja kurkkutautien klinikka, HUS.
Duodecim. 2012;128(2):219-24.
Nasal polyposis is an adult type mucosal inflammation of unknown etiology. Polyps are found in 4% of the Finns and in 17% of asthma patients. The first-line treatment is corticosteroid nasal spray and, if necessary, corticosteroid nasal drops or orally administered corticosteroids. Lavages with sodium chloride solution can be utilized as supportive therapy. A combination of antibiotics and corticosteroida is worthwhile in purulent rhinosinusitis. Surgery is contemplated, if conservative therapy is ineffective. In ASA-intolerant asthmatics nasal polyposis may be severe and recur in spite of drug and surgical therapy.
鼻息肉病是一种病因不明的成人型黏膜炎症。在4%的芬兰人和17%的哮喘患者中发现有息肉。一线治疗是使用糖皮质激素鼻喷雾剂,必要时可使用糖皮质激素滴鼻剂或口服糖皮质激素。可用氯化钠溶液冲洗作为辅助治疗。对于化脓性鼻窦炎,抗生素和糖皮质激素联合使用是值得的。如果保守治疗无效,则考虑手术。在阿司匹林不耐受的哮喘患者中,尽管进行了药物和手术治疗,鼻息肉病仍可能很严重且会复发。