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[The effect of corticoids on bone tissue in myasthenia gravis].

作者信息

Zejkan A D, Bakosová M, Vrbová H, Pesková M, Bejcek Z, Horejs J

机构信息

I. chirurgická klinika fakulty vseobecného lékarství Univerzity Karlovy, Praha.

出版信息

Sb Lek. 1990 Jul;92(6-7):194-202.

PMID:2237235
Abstract

Myasthenia gravis is an autoimmune disease where corticoids are the basis of therapy. They are taken for short periods in large amounts, as well as for prolonged periods in medium or small doses. The authors investigated in the described groups the effect of corticoids on bone tissue. They provided evidence of a significant effect on the diffraction pattern, geometrical arrangement of the apatite grid and ion changes in relation to the period of corticoid administration without significant clinical manifestations of osteoporosis, when respecting therapeutic principles.

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