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输尿管软镜与体外冲击波碎石术治疗 10-20mm 下极结石的比较。

Flexible ureterorenoscopy versus extracorporeal shock wave lithotripsy for treatment of lower pole stones of 10-20 mm.

机构信息

Urology Department, Urology and Nephrology Center, Mansoura University, Egypt.

出版信息

BJU Int. 2012 Sep;110(6):898-902. doi: 10.1111/j.1464-410X.2012.10961.x. Epub 2012 Feb 28.

Abstract

UNLABELLED

What's known on the subject? and What does the study add? Shock wave lithotripsy and flexible ureterorenoscopy are acceptable treatment options for lower pole stones smaller than 10 mm, while percutaneous nephrolithotomy is the favoured treatment for stones larger than 20 mm. For treatment of lower pole stones of 10-20 mm, flexible ureterorenoscopy has a significantly higher stone-free rate and lower retreatment rate than shock wave lithotripsy.

OBJECTIVE

To compare the outcomes of flexible ureterorenoscopy (F-URS) and extracorporeal shock wave lithotripsy (ESWL) for treatment of lower pole stones of 10-20 mm.

PATIENTS AND METHODS

The database of patients with a single lower pole stone of 10-20 mm was examined to obtain two matched groups who were treated with F-URS or ESWL. Matching criteria were stone length, side and patient gender. Stone-free rates were evaluated 3 months after the last treatment session by non-contrast computed tomography. Both groups were compared for retreatment rate, complications and stone-free rate.

RESULTS

The matched groups included 37 patients who underwent F-URS and 62 patients who underwent ESWL. Retreatment rate was significantly higher for ESWL (60% vs 8%, P < 0.001). Complications were more after F-URS (13.5% vs 4.8%), but the difference was not significant (P= 0.146). All complications were grade II or IIIa on modified Clavien classification. The stone-free rate was significantly better after F-URS (86.5% vs 67.7%, P= 0.038). One failure of F-URS (2.7%) and five failures (8%) of ESWL were treated with percutaneous nephrolithotomy. Significant residual fragments in three patients (8%) after F-URS were treated with ESWL, while significant residual fragments after ESWL in five patients (8%) were treated with F-URS. Residual fragments (<4 mm) were followed every 3 months in one patient (2.7%) after F-URS and in 10 patients (16%) after ESWL.

CONCLUSIONS

For treatment of lower pole stones of 10-20 mm, F-URS provided significantly higher stone-free rate and lower retreatment rate compared with ESWL. The incidence of complications after F-URS was not significantly more than after ESWL.

摘要

目的

比较输尿管软镜碎石术(F-URS)和体外冲击波碎石术(ESWL)治疗 10-20mm 下盏结石的效果。

方法

检查数据库中患有单个 10-20mm 下盏结石的患者,获得接受 F-URS 或 ESWL 治疗的两组匹配患者。匹配标准为结石长度、侧别和患者性别。末次治疗后 3 个月,采用非增强 CT 评估结石清除率。比较两组的复发率、并发症发生率和结石清除率。

结果

匹配的 F-URS 组和 ESWL 组各纳入 37 例和 62 例患者。ESWL 组的复发率显著更高(60%比 8%,P<0.001)。F-URS 组的并发症更多(13.5%比 4.8%,P=0.146),但差异无统计学意义。所有并发症均按改良 Clavien 分级为Ⅱ级或Ⅲa 级。F-URS 组的结石清除率显著更高(86.5%比 67.7%,P=0.038)。1 例 F-URS 治疗失败(2.7%)和 5 例 ESWL 治疗失败(8%)改行经皮肾镜取石术。3 例 F-URS 后有显著残石(8%)行 ESWL 治疗,5 例 ESWL 后有显著残石(8%)行 F-URS 治疗。F-URS 后 1 例患者(2.7%)和 ESWL 后 10 例患者(16%)有<4mm 的残石,每 3 个月随访 1 次。

结论

对于治疗 10-20mm 下盏结石,F-URS 与 ESWL 相比,结石清除率更高,复发率更低。F-URS 后并发症的发生率与 ESWL 后相比无显著增加。

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