Schilling D, Gakis G, Walcher U, Germann M, Stenzl A, Nagele Udo
Klinik für Urologie, Universitätsklinikum Tübingen.
Aktuelle Urol. 2009 Nov;40(6):351-4. doi: 10.1055/s-0029-1224680. Epub 2009 Sep 30.
The optimal treatment options for lower pole stones with a diameter below 15 mm are controversially discussed. Extracorporeal shock wave lithotripsy (ESWL) is non-invasive but is hampered by low stone-free rates and a significant retreatment rate. Flexible ureterorenoscopy (URS) has been demonstrated to have high stone-free rates but the treatment costs - consisting of OR time, repair costs and expenditure for laser fibers, guide wires and stone baskets - as well as low stone-free rates with increasing stone size render this procedure highly expensive. Minimally invasive percutaneous litholapaxy (MIP) has shown low morbidity and high efficacy in the treatment of nephrolithiasis. The goal of this study was to investigate the efficacy and -safety of MIP for the treatment of small lower pole stones.
The charts of 29 patients who were treated with MIP were reviewed and clinical data like OR time, drop in haemoglobin, complication rate, stone-free rate and duration of hospital stay were collected.
28 of 29 patients were primarily stone-free; one had to undergo additional flexible URS to become stone-free. All procedures were undertaken with only one access, no severe complications occurred; none of the patients had to be transfused.
The MIP concept has a low complication rate and has been shown to be safe and effective in previous studies. We demonstrate that the feasibility and efficacy justify the percutaneous approach also for small lower pole stones.
对于直径小于15毫米的下极结石,最佳治疗方案存在争议。体外冲击波碎石术(ESWL)是非侵入性的,但结石清除率低且再次治疗率高,限制了其应用。软性输尿管肾镜检查(URS)已被证明具有较高的结石清除率,但治疗成本(包括手术时间、修复成本以及激光纤维、导丝和取石篮的费用)较高,且随着结石尺寸增大结石清除率降低,使得该手术费用高昂。微创经皮肾镜取石术(MIP)在肾结石治疗中显示出低发病率和高疗效。本研究的目的是探讨MIP治疗下极小结石的疗效和安全性。
回顾了29例行MIP治疗患者的病历,并收集了诸如手术时间、血红蛋白下降情况、并发症发生率、结石清除率和住院时间等临床数据。
29例患者中有28例初次手术后结石清除;1例患者需额外接受软性URS治疗才能清除结石。所有手术均通过单一通道完成,未发生严重并发症;无一例患者需要输血。
MIP理念并发症发生率低,且在先前研究中已证明安全有效。我们证明,对于下极小结石,经皮手术方法的可行性和疗效是合理的。