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逆行性肾内手术与超声引导下冲击波碎石术治疗1至2厘米透X线的下盏结石的对比研究

Comparative study between retrograde intrarenal surgery and ultrasound- guided shock wave lithotripsy for treatment of 1 to 2 cm radiolucent lower calyceal stones.

作者信息

Elal Ashraf M Abd, Shaher Hussein, El-Barky Ehab, Ali Saad, Omar Rabea Gomaa

机构信息

Department of Urology, Faculty of Medicine, Benha University, Benha, Egypt.

出版信息

Urol Ann. 2024 Jul-Sep;16(3):185-191. doi: 10.4103/ua.ua_5_24. Epub 2024 Jun 10.

Abstract

OBJECTIVES

The objective is to compare the safety and efficacy of retrograde intrarenal surgery (RIRS) and ultrasound-guided (US-guided) shock wave lithotripsy (SWL) for the treatment of radiolucent lower pole calculi of 1-2 cm.

MATERIALS AND METHODS

This prospective randomized study was performed at our tertiary care urology institute of Benha University Hospitals; cases were randomized either to undergo RIRS (Group A) or US-guided SWL with a triple focus system (Group B). The safety and effectiveness of both therapies were compared using new criteria for stone-free rate (SFR): Grade A (absolutely stone free), Grade B (≤2 mm fragments), and Grade C (>2 mm up to 4 mm fragments), fluoroscopy time, operative time, auxiliary procedures, retreatment, and complications.

RESULTS

Out of 100 patients, 92 were eligible for this study. RIRS had a higher SFR of 88.9% compared to SWL, 72.3% ( = 0.045). Furthermore, stone-free classification significantly differed between the studied groups ( < 0.001), with Grade A being significantly higher in Group A. Conversely, Grades B and C were lower in Group A. On the other hand, operative and fluoroscopy times were significantly reduced with SWL ( = 0.004 and < 0.001, respectively). While complications did not significantly differ between the two groups ( = 0.340), a significant distinction was observed in terms of the Clavien-Dindo classification.

CONCLUSIONS

RIRS is an effective and safe option for treating radiolucent lower calyceal stones of ≤2 cm, with a greater SFR and lower need for auxiliary operations. However, Sono SWL is a cost-effective alternative that can achieve a comparable success rate after retreatment sessions.

摘要

目的

比较逆行肾内手术(RIRS)和超声引导(US引导)冲击波碎石术(SWL)治疗1-2cm透光性下极结石的安全性和有效性。

材料与方法

本前瞻性随机研究在本哈大学医院三级泌尿外科机构进行;病例随机分为接受RIRS治疗组(A组)或采用三焦点系统的US引导SWL治疗组(B组)。使用结石清除率(SFR)的新标准比较两种治疗方法的安全性和有效性:A级(结石完全清除)、B级(≤2mm碎片)和C级(>2mm至4mm碎片)、透视时间、手术时间、辅助操作、再次治疗和并发症。

结果

100例患者中,92例符合本研究条件。与SWL的72.3%相比,RIRS的SFR更高,为88.9%(P=0.045)。此外,研究组之间的结石清除分类有显著差异(P<0.001),A组的A级明显更高。相反,A组的B级和C级较低。另一方面,SWL的手术和透视时间显著缩短(分别为P=0.004和P<0.001)。虽然两组之间的并发症无显著差异(P=0.340),但在Clavien-Dindo分类方面观察到显著差异。

结论

RIRS是治疗≤2cm透光性下盏结石的有效且安全的选择,结石清除率更高,辅助手术需求更低。然而,超声SWL是一种具有成本效益的替代方法,在再次治疗后可获得相当的成功率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5da8/11404710/b51cf4cb835a/UA-16-185-g001.jpg

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