Romanos G E, Schröter-Kermani C, Hinz N, Wachtel H C, Bernimoulin J P
Abteilung für Parodontologie, Freie Universität Berlin.
Schweiz Monatsschr Zahnmed. 1990;100(9):1049-52.
The distribution of the collagen types I, III, IV, V, VI and of the glycoprotein laminin have been examined in the healthy gingiva of the marmoset with the indirect immunofluorescence method. It has been shown that collagen type I formed thick fibrils in a wave-like pattern, while collagen type III formed thinner fibrils, especially under the epithelial basal membrane. Collagen type IV and laminin showed a strong fluorescence in the basal membrane (epithelium, vessels, nerves). Collagen type V has been demonstrated as a fine fibrillar pattern in the lamina propria and occasionally close to the basal membrane. Collagen type VI has been represented as a microfibrillar network in the connective tissue matrix with a brilliant pericellular fluorescence around vessels and nerves. The study showed the structural model of the connective tissue matrix of the marmoset gingiva and allows a later comparison between inflamed and healthy gingiva.
采用间接免疫荧光法检测了狨猴健康牙龈中I型、III型、IV型、V型、VI型胶原蛋白及糖蛋白层粘连蛋白的分布情况。结果显示，I型胶原蛋白形成呈波浪状的粗大纤维，而III型胶原蛋白形成较细的纤维，尤其是在上皮基底膜下方。IV型胶原蛋白和层粘连蛋白在基底膜（上皮、血管、神经）处呈现强荧光。V型胶原蛋白在固有层表现为细纤维状模式，偶尔靠近基底膜。VI型胶原蛋白在结缔组织基质中表现为微纤维网络，血管和神经周围有明亮的细胞周围荧光。该研究展示了狨猴牙龈结缔组织基质的结构模型，便于日后对炎症牙龈和健康牙龈进行比较。
